Literature DB >> 8063430

Relationship between superoxide dismutase and melanin in a pathogenic fungus.

E S Jacobson1, N D Jenkins, J M Todd.   

Abstract

Since melanin is considered a virulence factor in Cryptococcus neoformans, its suppression at 37 degrees C has been perplexing. We now show an opposite thermal regulation of superoxide dismutase (SOD), consistent with a compensatory mechanism. Moreover, we demonstrate normal SOD and catalase levels in albino, oxygen-sensitive mutants. These results suggest that melanin is an antioxidant factor comparable in importance to SOD.

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Year:  1994        PMID： 8063430      PMCID： PMC303074          DOI： 10.1128/iai.62.9.4085-4086.1994

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  16 in total

1.  Free radicals in biological materials.

Authors:  B COMMONER; J TOWNSEND; G E PAKE
Journal:  Nature       Date:  1954-10-09       Impact factor: 49.962

2.  Catecholamines and virulence of Cryptococcus neoformans.

Authors:  I Polacheck; Y Platt; J Aronovitch
Journal:  Infect Immun       Date:  1990-09       Impact factor: 3.441

3.  Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent.

Authors:  B M Babior; R S Kipnes; J T Curnutte
Journal:  J Clin Invest       Date:  1973-03       Impact factor: 14.808

4.  Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice.

Authors:  K J Kwon-Chung; I Polacheck; T J Popkin
Journal:  J Bacteriol       Date:  1982-06       Impact factor: 3.490

5.  Genetic and phenotypic characterization of capsule mutants of Cryptococcus neoformans.

Authors:  E S Jacobson; D J Ayers; A C Harrell; C C Nicholas
Journal:  J Bacteriol       Date:  1982-06       Impact factor: 3.490

6.  An enzyme-based theory of obligate anaerobiosis: the physiological function of superoxide dismutase.

Authors:  J M McCord; B B Keele; I Fridovich
Journal:  Proc Natl Acad Sci U S A       Date:  1971-05       Impact factor: 11.205

7.  Studies on the chlorinating activity of myeloperoxidase.

Authors:  J E Harrison; J Schultz
Journal:  J Biol Chem       Date:  1976-03-10       Impact factor: 5.157

8.  New, special stain for histopathological diagnosis of cryptococcosis.

Authors:  K J Kwon-Chung; W B Hill; J E Bennett
Journal:  J Clin Microbiol       Date:  1981-02       Impact factor: 5.948

9.  Pathogenicity and virulence of wild-type and melanin-deficient Wangiella dermatitidis.

Authors:  D M Dixon; A Polak; P J Szaniszlo
Journal:  J Med Vet Mycol       Date:  1987-04

10.  Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation.

Authors:  S J Weiss; R Klein; A Slivka; M Wei
Journal:  J Clin Invest       Date:  1982-09       Impact factor: 14.808
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  25 in total

Review 1.  Pathogenic roles for fungal melanins.

Authors:  E S Jacobson
Journal:  Clin Microbiol Rev       Date:  2000-10       Impact factor: 26.132

2.  Melanin, melanin "ghosts," and melanin composition in Cryptococcus neoformans.

Authors:  Y Wang; P Aisen; A Casadevall
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

Review 3.  Impact of melanin on microbial virulence and clinical resistance to antimicrobial compounds.

Authors:  Joshua D Nosanchuk; Arturo Casadevall
Journal:  Antimicrob Agents Chemother       Date:  2006-11       Impact factor: 5.191

4.  Catecholamine oxidative products, but not melanin, are produced by Cryptococcus neoformans during neuropathogenesis in mice.

Authors:  L Liu; K Wakamatsu; S Ito; P R Williamson
Journal:  Infect Immun       Date:  1999-01       Impact factor: 3.441

Review 5.  Continuing to illuminate the mechanisms underlying UV-mediated melanomagenesis.

Authors:  Ryan W Dellinger; Feng Liu-Smith; Frank L Meyskens
Journal:  J Photochem Photobiol B       Date:  2014-06-20       Impact factor: 6.252

6.  Genetic study of oxygen resistance and melanization in Cryptococcus neoformans.

Authors:  H S Emery; C P Shelburne; J P Bowman; P G Fallon; C A Schulz; E S Jacobson
Journal:  Infect Immun       Date:  1994-12       Impact factor: 3.441

7.  Melanin production by a filamentous soil fungus in response to copper and localization of copper sulfide by sulfide-silver staining.

Authors:  T Caesar-Tonthat; K F Van Ommen; G G Geesey; J M Henson
Journal:  Appl Environ Microbiol       Date:  1995-05       Impact factor: 4.792

8.  Effect of different K+ concentrations on Cryptococcus neoformans phenoloxidase activity.

Authors:  Valerio Vidotto; Nicola Defina; Agostino Pugliese; Shigeji Aoki; Kenjrou Nakamura; Kanjj Takeo
Journal:  Mycopathologia       Date:  2002       Impact factor: 2.574

9.  Superoxide dismutase influences the virulence of Cryptococcus neoformans by affecting growth within macrophages.

Authors:  Gary M Cox; Thomas S Harrison; Henry C McDade; Carlos P Taborda; Garrett Heinrich; Arturo Casadevall; John R Perfect
Journal:  Infect Immun       Date:  2003-01       Impact factor: 3.441

10.  Melanosomal damage in normal human melanocytes induced by UVB and metal uptake--a basis for the pro-oxidant state of melanoma.

Authors:  Shirley Gidanian; Mallory Mentelle; Frank L Meyskens; Patrick J Farmer
Journal:  Photochem Photobiol       Date:  2008-03-07       Impact factor: 3.421
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