Literature DB >> 8063427

Humoral immune response to the Trypanosoma cruzi complement regulatory protein as an indicator of parasitologic clearance in human Chagas' disease.

K A Norris1, L M Galvão, J E Schrimpf, J R Cançado, A U Krettli.   

Abstract

Immunoprecipitation of the purified 160-kDa complement regulatory protein of Trypanosoma cruzi by Chagas' disease patient sera was examined as a possible correlate of the complement-mediated lysis test and as an indicator of parasite clearance. The results presented demonstrate that assessment of the humoral response to this antigen is a useful indicator of parasite clearance and may be particularly helpful in the assessment of some patients for whom other serological tests produce ambiguous results.

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Year:  1994        PMID： 8063427      PMCID： PMC303071          DOI： 10.1128/iai.62.9.4072-4074.1994

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  12 in total

1.  Evasion of Trypanosoma cruzi from complement lysis.

Authors:  T L Kipnis; W D da Silva
Journal:  Braz J Med Biol Res       Date:  1989       Impact factor: 2.590

Review 2.  Identification and analysis of glycoinositol phospholipid anchors in membrane proteins.

Authors:  T L Rosenberry; J P Toutant; R Haas; W L Roberts
Journal:  Methods Cell Biol       Date:  1989       Impact factor: 1.441

3.  Lytic antibody titre as a means of assessing cure after treatment of Chagas disease: a 10 years follow-up study.

Authors:  L M Galvao; R M Nunes; J R Cançado; Z Brener; A U Krettli
Journal:  Trans R Soc Trop Med Hyg       Date:  1993 Mar-Apr       Impact factor: 2.184

4.  Effect of specific chemotherapy on the levels of lytic antibodies in Chagas's disease.

Authors:  A U Krettli; J R Cançado; Z Brener
Journal:  Trans R Soc Trop Med Hyg       Date:  1982       Impact factor: 2.184

5.  Characterization of a Trypanosoma cruzi C3 binding protein with functional and genetic similarities to the human complement regulatory protein, decay-accelerating factor.

Authors:  K A Norris; B Bradt; N R Cooper; M So
Journal:  J Immunol       Date:  1991-10-01       Impact factor: 5.422

6.  Hemocultures for the parasitological diagnosis of human chronic Chagas' disease.

Authors:  E Chiari; J C Dias; M Lana; C A Chiari
Journal:  Rev Soc Bras Med Trop       Date:  1989 Jan-Mar       Impact factor: 1.581

7.  Purification of a Trypanosoma cruzi membrane glycoprotein which elicits lytic antibodies.

Authors:  K A Norris; G Harth; M So
Journal:  Infect Immun       Date:  1989-08       Impact factor: 3.441

8.  Developmentally regulated expression by Trypanosoma cruzi of molecules that accelerate the decay of complement C3 convertases.

Authors:  M T Rimoldi; A Sher; S Heiny; A Lituchy; C H Hammer; K Joiner
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

9.  Biochemical analysis of the membrane and soluble forms of the complement regulatory protein of Trypanosoma cruzi.

Authors:  K A Norris; J E Schrimpf
Journal:  Infect Immun       Date:  1994-01       Impact factor: 3.441

10.  Human and mouse sera recognize the same polypeptide associated with immunological resistance to Trypanosoma cruzi infection.

Authors:  M S Martins; L Hudson; A U Krettli; J R Cançado; Z Brener
Journal:  Clin Exp Immunol       Date:  1985-08       Impact factor: 4.330
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  8 in total

1.  Use of the Trypanosoma cruzi recombinant complement regulatory protein to evaluate therapeutic efficacy following treatment of chronic chagasic patients.

Authors:  Wendell S F Meira; Lúcia M C Galvão; Eliane D Gontijo; George L L Machado-Coelho; Karen A Norris; Egler Chiari
Journal:  J Clin Microbiol       Date:  2004-02       Impact factor: 5.948

2.  Stable transfection of Trypanosoma cruzi epimastigotes with the trypomastigote-specific complement regulatory protein cDNA confers complement resistance.

Authors:  K A Norris
Journal:  Infect Immun       Date:  1998-06       Impact factor: 3.441

3.  Identification of the gene family encoding the 160-kilodalton Trypanosoma cruzi complement regulatory protein.

Authors:  K A Norris; J E Schrimpf; M J Szabo
Journal:  Infect Immun       Date:  1997-02       Impact factor: 3.441

4.  DNA-Based immunization with Trypanosoma cruzi complement regulatory protein elicits complement lytic antibodies and confers protection against Trypanosoma cruzi infection.

Authors:  P Sepulveda; M Hontebeyrie; P Liegeard; A Mascilli; K A Norris
Journal:  Infect Immun       Date:  2000-09       Impact factor: 3.441

5.  Use of a 24-kilodalton Trypanosoma cruzi recombinant protein to monitor cure of human Chagas' disease.

Authors:  G M Krautz; L M Galvão; J R Cançado; A Guevara-Espinoza; A Ouaissi; A U Krettli
Journal:  J Clin Microbiol       Date:  1995-08       Impact factor: 5.948

6.  Sequence diversity of the Trypanosoma cruzi complement regulatory protein family.

Authors:  M Beucher; K A Norris
Journal:  Infect Immun       Date:  2007-12-10       Impact factor: 3.441

7.  Trypanosoma cruzi recombinant complement regulatory protein: a novel antigen for use in an enzyme-linked immunosorbent assay for diagnosis of Chagas' disease.

Authors:  Wendell S F Meira; Lúcia M C Galvão; Eliane D Gontijo; George L L Machado-Coelho; Karen A Norris; Egler Chiari
Journal:  J Clin Microbiol       Date:  2002-10       Impact factor: 5.948

Review 8.  The Complement System: A Prey of Trypanosoma cruzi.

Authors:  Kárita C F Lidani; Lorena Bavia; Altair R Ambrosio; Iara J de Messias-Reason
Journal:  Front Microbiol       Date:  2017-04-20       Impact factor: 5.640
  8 in total

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