| Literature DB >> 8063252 |
A M Khalil1, B I Yamout, S D Tabbal, Z M Salem, A M Mroueh.
Abstract
The diagnosis of leptomeningeal relapse in a patient with epithelial ovarian cancer was confirmed by the presence of malignant ovarian cells in the cerebrospinal fluid. There was no clinical evidence of tumor spread elsewhere. Therapy, including intrathecal methotrexate and whole-brain irradiation led to transient clinical improvement. International literature review revealed only 13 other cases of leptomeningeal carcinomatosis in epithelial ovarian cancer; all died within 15 months following the diagnosis of leptomeningeal spread.Entities:
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Year: 1994 PMID： 8063252 DOI： 10.1006/gyno.1994.1199
Source DB: PubMed Journal: Gynecol Oncol ISSN： 0090-8258 Impact factor: 5.482