Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Iron deprivation-induced apoptosis in HL-60 cells.

Literature DB >> 8062913

Iron deprivation-induced apoptosis in HL-60 cells.

K Fukuchi¹, S Tomoyasu, N Tsuruoka, K Gomi.

Abstract

Iron deprivation of HL-60 cells with deferoxamine B mesylate (DFO) induced apoptosis. DNA fragmentation became apparent with 10(-6) M DFO after 48 h treatment. The apoptosis peak according to the DNA histogram on flow cytometry and typical nuclear collapse and were observed microscopically after 48 h treatment with 10(-4) M DFO. Cells treated with 10(-4) M DFO for as little as 24 h were shown to be committed to apoptosis, as chromatin condensation progressed gradually thereafter.

Entities: Chemical

Mesh：

Substances：

Year: 1994 PMID： 8062913 DOI： 10.1016/0014-5793(94)00755-1

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

Keyword Cloud
Cited

17 in total

1. Unexpected effects of albumin on apoptosis induction by deferoxamine in vitro.

Authors: J Kovár; J D Kemp
Journal: In Vitro Cell Dev Biol Anim Date: 2000-03 Impact factor: 2.416

2. The iron chelator deferoxamine causes activated hepatic stellate cells to become quiescent and to undergo apoptosis.

Authors: Haiyan Jin; Shuji Terai; Isao Sakaida
Journal: J Gastroenterol Date: 2007-06-29 Impact factor: 7.527

3. Apoptosis of acinar cells in rat pancreatic duct ligation.

Authors: M Wada; R Doi; R Hosotani; J U Lee; M Imamura
Journal: J Gastroenterol Date: 1995-12 Impact factor: 7.527

4. Investigating the parameters affecting the stability of superparamagnetic iron oxide-loaded nanoemulsion using artificial neural networks.

Authors: Gholamreza Ahmadi Lakalayeh; Reza Faridi-Majidi; Reza Saber; Alireza Partoazar; Shahram Ejtemaei Mehr; Amir Amani
Journal: AAPS PharmSciTech Date: 2012-10-09 Impact factor: 3.246

5. Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1.

Authors: Yu Yu; Des R Richardson
Journal: J Biol Chem Date: 2011-03-05 Impact factor: 5.157

10. 1,10-Phenanthroline stimulates internucleosomal DNA fragmentation in isolated rat-liver nuclei by promoting the redox activity of endogenous copper ions.

Authors: M J Burkitt; L Milne; P Nicotera; S Orrenius
Journal: Biochem J Date: 1996-01-01 Impact factor: 3.857

Iron deprivation-induced apoptosis in HL-60 cells.

1. Unexpected effects of albumin on apoptosis induction by deferoxamine in vitro.

2. The iron chelator deferoxamine causes activated hepatic stellate cells to become quiescent and to undergo apoptosis.

3. Apoptosis of acinar cells in rat pancreatic duct ligation.

4. Investigating the parameters affecting the stability of superparamagnetic iron oxide-loaded nanoemulsion using artificial neural networks.

5. Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1.

6. Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro.

7. Sensitivity of cells to apoptosis induced by iron deprivation can be reversibly changed by iron availability.

8. The effects of iron deficiency on neutrophil/monocyte apoptosis in children.

Review 9. Air pollutants disrupt iron homeostasis to impact oxidant generation, biological effects, and tissue injury.

10. 1,10-Phenanthroline stimulates internucleosomal DNA fragmentation in isolated rat-liver nuclei by promoting the redox activity of endogenous copper ions.