Literature DB >> 8061939

Regional variation in the presence of canebrake toxin in Crotalus horridus venom.

J L Glenn1, R C Straight, T B Wolt.   

Abstract

Reverse-phase HPLC was used to isolate the PLA complex neurotoxin "canebrake toxin" from the venom of Crotalus horridus from northern Florida. Individual venoms from 107 specimens of C. horridus throughout its range were investigated for the presence of the toxin. The distribution of canebrake toxin was limited to two separate regions, including a region of Louisiana, Arkansas and Oklahoma, and a separate region from southeastern South Carolina through eastern Georgia to northern Florida. Four distinct venom types were found and designated Venoms A (neurotoxic), B (hemorrhagic), A + B (neurotoxic and hemorrhagic) and C (lacking in both neurotoxic and hemorrhagic activities).

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Year:  1994        PMID： 8061939     DOI： 10.1016/1367-8280(94)90059-0

Source DB:  PubMed          Journal:  Comp Biochem Physiol Pharmacol Toxicol Endocrinol


  18 in total

1.  Extremely Divergent Haplotypes in Two Toxin Gene Complexes Encode Alternative Venom Types within Rattlesnake Species.

Authors:  Noah L Dowell; Matt W Giorgianni; Sam Griffin; Victoria A Kassner; Jane E Selegue; Elda E Sanchez; Sean B Carroll
Journal:  Curr Biol       Date:  2018-03-22       Impact factor: 10.834

2.  Snake venomics of Crotalus tigris: the minimalist toxin arsenal of the deadliest Nearctic rattlesnake venom. Evolutionary Clues for generating a pan-specific antivenom against crotalid type II venoms [corrected].

Authors:  Juan J Calvete; Alicia Pérez; Bruno Lomonte; Elda E Sánchez; Libia Sanz
Journal:  J Proteome Res       Date:  2012-01-09       Impact factor: 4.466

3.  Neurotoxic snakes of the Americas.

Authors:  Terry D Rolan
Journal:  Neurol Clin Pract       Date:  2015-10

4.  Molecular evolution and structure-function relationships of crotoxin-like and asparagine-6-containing phospholipases A2 in pit viper venoms.

Authors:  Yi-Hsuan Chen; Ying-Ming Wang; Ming-Jhy Hseu; Inn-Ho Tsai
Journal:  Biochem J       Date:  2004-07-01       Impact factor: 3.857

5.  The Deep Origin and Recent Loss of Venom Toxin Genes in Rattlesnakes.

Authors:  Noah L Dowell; Matt W Giorgianni; Victoria A Kassner; Jane E Selegue; Elda E Sanchez; Sean B Carroll
Journal:  Curr Biol       Date:  2016-09-15       Impact factor: 10.834

6.  The Tiger Rattlesnake genome reveals a complex genotype underlying a simple venom phenotype.

Authors:  Mark J Margres; Rhett M Rautsaw; Jason L Strickland; Andrew J Mason; Tristan D Schramer; Erich P Hofmann; Erin Stiers; Schyler A Ellsworth; Gunnar S Nystrom; Michael P Hogan; Daniel A Bartlett; Timothy J Colston; David M Gilbert; Darin R Rokyta; Christopher L Parkinson
Journal:  Proc Natl Acad Sci U S A       Date:  2021-01-26       Impact factor: 12.779

7.  Post-transcriptional Mechanisms Contribute Little to Phenotypic Variation in Snake Venoms.

Authors:  Darin R Rokyta; Mark J Margres; Kate Calvin
Journal:  G3 (Bethesda)       Date:  2015-09-09       Impact factor: 3.154

8.  Is Hybridization a Source of Adaptive Venom Variation in Rattlesnakes? A Test, Using a Crotalus scutulatus × viridis Hybrid Zone in Southwestern New Mexico.

Authors:  Giulia Zancolli; Timothy G Baker; Axel Barlow; Rebecca K Bradley; Juan J Calvete; Kimberley C Carter; Kaylah de Jager; John Benjamin Owens; Jenny Forrester Price; Libia Sanz; Amy Scholes-Higham; Liam Shier; Liam Wood; Catharine E Wüster; Wolfgang Wüster
Journal:  Toxins (Basel)       Date:  2016-06-16       Impact factor: 4.546

9.  The genesis of an exceptionally lethal venom in the timber rattlesnake (Crotalus horridus) revealed through comparative venom-gland transcriptomics.

Authors:  Darin R Rokyta; Kenneth P Wray; Mark J Margres
Journal:  BMC Genomics       Date:  2013-06-12       Impact factor: 3.969

10.  Full-Length Venom Protein cDNA Sequences from Venom-Derived mRNA: Exploring Compositional Variation and Adaptive Multigene Evolution.

Authors:  Cassandra M Modahl; Stephen P Mackessy
Journal:  PLoS Negl Trop Dis       Date:  2016-06-09
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