Literature DB >> 8059048

[Freeman-Sheldon syndrome: generalized muscular rigidity after anesthetic induction].

C G Sobrado1, M Ribera, M Martí, J Erdocia, R Rodríguez.   

Abstract

We describe a case of generalized muscle rigidity in a 2-year-old patient with Freeman-Sheldon syndrome undergoing surgery for eventration of the diaphragm after anesthetic induction with halothane and succinylcholine. Anesthetic induction was by mask with oxygen, nitrous oxide and halothane, with succinylcholine as a muscle relaxant. Approximately 10 minutes after start of induction, muscular rigidity appeared and developed rapidly, becoming severe and compromising ventilation. Tracheal intubation was attempted without success, owing to stiffness of the masseter muscles. Sodium dantrolene 2.5 mg/kg was administered and relaxation was achieved immediately for both masseter and peripheral muscles, such that the patient recovered spontaneous breathing. We conclude that there is risk of association between Freeman-Sheldon syndrome and malignant hyperthermia.

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Year:  1994        PMID: 8059048

Source DB:  PubMed          Journal:  Rev Esp Anestesiol Reanim        ISSN: 0034-9356


  4 in total

Review 1.  Freeman-sheldon syndrome presenting with microstomia: a case report and literature review.

Authors:  Vivek Gurjar; Anita Parushetti; Minal Gurjar
Journal:  J Maxillofac Oral Surg       Date:  2012-05-17

2.  Freeman-Sheldon Syndrome: First Molecularly Confirmed Case from Sub-Saharan Africa.

Authors:  A M Ali; R M Mbwasi; G Kinabo; E-J Kamsteeg; B C Hamel; M C J Dekker
Journal:  Case Rep Genet       Date:  2017-05-11

3.  Emergent Cesarean Delivery in a Patient With Freeman-Sheldon Syndrome Complicated by Preeclampsia, Acute Pulmonary Embolism, and Pulmonary Edema: A Case Report.

Authors:  Mohamed Fayed; Mark A Giska; Rebekah C Shievitz; Ami Attali; Joshua Younger
Journal:  Cureus       Date:  2021-12-29

4.  Freeman-Sheldon Syndrome with Stiff Knee Gait - A Case Report.

Authors:  Sandeep Sehrawat; Sumit Sural; Pon Aravindhan A Sugumar; Shahrukh Khan; Santanu Kar; Madhan Jeyaraman
Journal:  J Orthop Case Rep       Date:  2021-11
  4 in total

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