| Literature DB >> 8058157 |
H Ito1, S Sayama, S Irie, N Kanazawa, T Saito, H Kowa, S Haga, K Ikeda.
Abstract
A 29-year-old man developed acute cerebellar ataxia following Epstein-Barr virus infection. Serum IgG and IgM antibodies reacted with both nuclear and cytoplasmic elements of neurons. Western blot revealed IgG binding to the 34- and 29-kd bands and IgM binding to the 44-, 37-, and 29-kd bands. The IgM reactivity gradually reduced. There was no identifiable neoplasm and the ataxia gradually improved. These findings suggest a role for autoimmune mechanisms in the pathogenesis of acute cerebellar ataxia.Entities:
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Year: 1994 PMID: 8058157 DOI: 10.1212/wnl.44.8.1506
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910