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Literature DB >> 8057038

Genomic mismatch scanning in pedigrees.

Abstract

The new method of genomic mismatch scanning allows the high-resolution mapping of identity by descent on the chromosomes of two related individuals. Modelling recombinant events as a continuous Markov process, the authors design experiments and statistical tests for the use of this technique on sets of affected individuals in pedigrees in order to determine candidate regions for genes contributing to the disease.

Mesh：

Year: 1994 PMID： 8057038 DOI： 10.1093/imammb/11.1.1

Source DB: PubMed Journal: IMA J Math Appl Med Biol ISSN： 0265-0746

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Cited

19 in total

1. Shared genomic segment analysis. Mapping disease predisposition genes in extended pedigrees using SNP genotype assays.

Authors: A Thomas; N J Camp; J M Farnham; K Allen-Brady; L A Cannon-Albright
Journal: Ann Hum Genet Date: 2007-12-18 Impact factor: 1.670

2. A Nonsynonymous Variant in the GOLM1 Gene in Cutaneous Malignant Melanoma.

Authors: Craig C Teerlink; Chad Huff; Jeff Stevens; Yao Yu; Sheri L Holmen; Mark R Silvis; Kirby Trombetti; Hua Zhao; Douglas Grossman; James M Farnham; Jingran Wen; Julio C Facelli; Alun Thomas; Markus Babst; Scott R Florell; Laurence Meyer; John J Zone; Sancy Leachman; Lisa A Cannon-Albright
Journal: J Natl Cancer Inst Date: 2018-12-01 Impact factor: 13.506

3. A SNP streak model for the identification of genetic regions identical-by-descent.

Authors: Gregory Leibon; Daniel N Rockmore; Martin R Pollak
Journal: Stat Appl Genet Mol Biol Date: 2008-05-10

4. Maximum-likelihood estimation of recent shared ancestry (ERSA).

Authors: Chad D Huff; David J Witherspoon; Tatum S Simonson; Jinchuan Xing; W Scott Watkins; Yuhua Zhang; Therese M Tuohy; Deborah W Neklason; Randall W Burt; Stephen L Guthery; Scott R Woodward; Lynn B Jorde
Journal: Genome Res Date: 2011-02-08 Impact factor: 9.043

Genomic mismatch scanning in pedigrees.

1. Shared genomic segment analysis. Mapping disease predisposition genes in extended pedigrees using SNP genotype assays.

2. A Nonsynonymous Variant in the GOLM1 Gene in Cutaneous Malignant Melanoma.

3. A SNP streak model for the identification of genetic regions identical-by-descent.

4. Maximum-likelihood estimation of recent shared ancestry (ERSA).

5. Parametric and nonparametric linkage analysis: a unified multipoint approach.

6. Genome scanning for segments shared identical by descent among distant relatives in isolated populations.

7. Selection with recurrent backcrossing to develop congenic lines for quantitative trait loci analysis.

8. Combining information within and between pedigrees for mapping complex traits.

9. Robust Inference of Identity by Descent from Exome-Sequencing Data.

10. A Genealogical Look at Shared Ancestry on the X Chromosome.