Literature DB >> 805650

Antiplasmodial efficacy of 2,4--diaminopyrimidine0sylfonamide combinations, especially against chloroquine-resistant malaria.

I M Rollo.   

Abstract

This presentation deals with the historical development of the antifolate pyrimidines and related compounds, first as antimalarial substances and later as potent antibacterial agents. It describes the first quantitation of the combined action, through sequential blockade, of the substances with sulfonamides, and outlines the usefulness of the combinations in the therapy of normally sensitive and multiresistant strains of Plasmodium falciparum.

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Year:  1975        PMID： 805650      PMCID： PMC1956452     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN： 0008-4409            Impact factor:   8.262


  8 in total

1.  Potentiation of pyrimethamine by sulphadiazine in human malaria.

Authors:  M G HURLY
Journal:  Trans R Soc Trop Med Hyg       Date:  1959-09       Impact factor: 2.184

2.  Studies on analogs of purines and pyrimidines.

Authors:  G H HITCHINGS; G B ELION; E A FALCO; P B RUSSELL; H VANDERWERFF
Journal:  Ann N Y Acad Sci       Date:  1950-07-07       Impact factor: 5.691

3.  Sulfalene with pyrimethamine and chloroquine with pyrimethamine in single-dose treatment of Plasmodium falciparum infections. A trial in a rural population in northern Nigeria.

Authors:  J Storey; A Rossi-Espagnet; S P Mandel; T Matsushima; P Lietaert; D Thomas; S Brogger; C Duby; G Gramiccia
Journal:  Bull World Health Organ       Date:  1973       Impact factor: 9.408

4.  Treatment of acute falciparum malaria from Vietnam with trimethoprim and sulfalene.

Authors:  C J Canfield; E G Whiting; W H Hall; B S MacDonald
Journal:  Am J Trop Med Hyg       Date:  1971-07       Impact factor: 2.345

5.  Sulfalene and trimethoprim in acute falciparum malaria.

Authors:  D F Clyde
Journal:  JAMA       Date:  1969-07-28       Impact factor: 56.272

6.  The evaluation of sulfonamides, alone or in combination with pyrimethamine, in the treatment of multi-resistant falciparum malaria.

Authors:  W Chin; P G Contacos; G R Coatney; H K King
Journal:  Am J Trop Med Hyg       Date:  1966-11       Impact factor: 2.345

Review 7.  Dihydrofolate reductase inhibitors as antimicrobial agents and their potentiation by sulfonamides.

Authors:  I M Rollo
Journal:  CRC Crit Rev Clin Lab Sci       Date:  1970-12

8.  Antimalarial activity of Kelfizina-trimethoprim and Kelfizina-pyrimethamine versus chloroquine in field trials in Nigeria.

Authors:  L Donno; V Sanguineti; M L Ricciardi; M Soldati
Journal:  Am J Trop Med Hyg       Date:  1969-03       Impact factor: 2.345
  8 in total
  3 in total

Review 1.  Co-trimoxazole (trimethoprim-sulfamethoxazole): an updated review of its antibacterial activity and clinical efficacy.

Authors:  G P Wormser; G T Keusch; R C Heel
Journal:  Drugs       Date:  1982-12       Impact factor: 9.546

2.  Efficacy of Pyrimethamine/Sulfadoxine versus Chloroquine for the Treatment of Uncomplicated Falciparum Malaria in Children Aged Under 5 Years.

Authors:  W Zheng; H Jiang; Z Xiong; Z Jiang; H Chen
Journal:  Iran J Parasitol       Date:  2013-01       Impact factor: 1.012

3.  Effect of iron/folic Acid supplementation on the outcome of malaria episodes treated with sulfadoxine-pyrimethamine.

Authors:  Sunil Sazawal; Robert E Black; Ibrahim Kabole; Arup Dutta; Usha Dhingra; Mahdi Ramsan
Journal:  Malar Res Treat       Date:  2014-01-19
  3 in total

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