Literature DB >> 8055180

Inhibitors of HIV-1 transcription.

C J Li1, B J Dezube, D K Biswas, C M Ahlers, A B Pardee.   

Abstract

No curative drug against HIV has yet been found, despite enormous efforts aimed at reverse transcriptase and a variety of other targets. The long terminal repeat (LTR) of HIV-1 has recently become a promising site for antiviral action. This article briefly summarizes information on the nature of this target and potential anti-LTR expression drugs.

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Year:  1994        PMID: 8055180     DOI: 10.1016/0966-842x(94)90666-1

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  2 in total

1.  Casein kinase II is a selective target of HIV-1 transcriptional inhibitors.

Authors:  J W Critchfield; J E Coligan; T M Folks; S T Butera
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-10       Impact factor: 11.205

2.  Compounds that target novel cellular components involved in HIV-1 transcription.

Authors:  S T Butera; B D Roberts; J W Critchfield; G Fang; T McQuade; S J Gracheck; T M Folks
Journal:  Mol Med       Date:  1995-11       Impact factor: 6.354

  2 in total

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