Literature DB >> 8055104

Reversed-phase chromatography of small molecules and peptides on a continuous rod of macroporous poly(styrene-co-divinylbenzene).

Q C Wang1, F Svec, J M Fréchet.   

Abstract

A continuous "molded" rod of porous poly(styrene-co-divinylbenzene) prepared by a bulk free radical polymerization within the confines of a chromatographic column has been used successfully for the reversed-phase HPLC of alkylbenzenes and peptides. An excellent rapid separation of bradykinin and [D-Phe7]-bradykinin with a molecular mass of about 1000 was also achieved.

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Year:  1994        PMID: 8055104     DOI: 10.1016/0021-9673(94)80352-8

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN: 0021-9673            Impact factor:   4.759


  7 in total

1.  Hypercrosslinking: new approach to porous polymer monolithic capillary columns with large surface area for the highly efficient separation of small molecules.

Authors:  Jiri Urban; Frantisek Svec; Jean M J Fréchet
Journal:  J Chromatogr A       Date:  2010-10-31       Impact factor: 4.759

Review 2.  Less common applications of monoliths. III. Gas chromatography.

Authors:  Frantisek Svec; Alexander A Kurganov
Journal:  J Chromatogr A       Date:  2007-07-13       Impact factor: 4.759

3.  Efficient separation of small molecules using a large surface area hypercrosslinked monolithic polymer capillary column.

Authors:  Jiri Urban; Frantisek Svec; Jean M J Fréchet
Journal:  Anal Chem       Date:  2010-03-01       Impact factor: 6.986

4.  Incorporation of carbon nanotubes in porous polymer monolithic capillary columns to enhance the chromatographic separation of small molecules.

Authors:  Stuart D Chambers; Frantisek Svec; Jean M J Fréchet
Journal:  J Chromatogr A       Date:  2011-03-17       Impact factor: 4.759

5.  Porous polymer monolithic column with surface-bound gold nanoparticles for the capture and separation of cysteine-containing peptides.

Authors:  Yan Xu; Qing Cao; Frantisek Svec; Jean M J Fréchet
Journal:  Anal Chem       Date:  2010-04-15       Impact factor: 6.986

6.  Optimization of the porous structure and polarity of polymethacrylate-based monolithic capillary columns for the LC-MS separation of enzymatic digests.

Authors:  Sebastiaan Eeltink; Laurent Geiser; Frantisek Svec; Jean M J Fréchet
Journal:  J Sep Sci       Date:  2007-11       Impact factor: 3.645

Review 7.  Porous polymer monoliths: amazingly wide variety of techniques enabling their preparation.

Authors:  Frantisek Svec
Journal:  J Chromatogr A       Date:  2009-10-02       Impact factor: 4.759

  7 in total

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