| Literature DB >> 8054542 |
J Spreer1, S Enenkel-Stoodt, M Funk, A Fiedler, A de Simone, H Hacker.
Abstract
The neuroradiological studies (CT, MRI, angiography) in 21 children with perinatal HIV infection were reviewed retrospectively. No patient showed an intracranial mass lesion; after intravenous contrast medium application there was no case with disturbed blood-brain barrier. Common non-specific findings were atrophy and delayed myelination. In 7 cases atrophy was combined with multifocal nearly symmetric white matter lesions, which characteristically spared the U-fibres. Further findings included an intramedullary ring-shaped structure in the cervical cord, an AIDS-associated vasculopathy and symmetric calcifications in the basal ganglia. The spectrum of neuroradiological findings in paediatric AIDS patients differs from that in adults. Knowledge of these age-specific findings is important because the number of HIV-infected children is rising.Entities:
Mesh:
Year: 1994 PMID: 8054542 DOI: 10.1055/s-2008-1032502
Source DB: PubMed Journal: Rofo ISSN: 1438-9010