Literature DB >> 8054542

[Neuroradiological findings in perinatally HIV-infected children].

J Spreer1, S Enenkel-Stoodt, M Funk, A Fiedler, A de Simone, H Hacker.   

Abstract

The neuroradiological studies (CT, MRI, angiography) in 21 children with perinatal HIV infection were reviewed retrospectively. No patient showed an intracranial mass lesion; after intravenous contrast medium application there was no case with disturbed blood-brain barrier. Common non-specific findings were atrophy and delayed myelination. In 7 cases atrophy was combined with multifocal nearly symmetric white matter lesions, which characteristically spared the U-fibres. Further findings included an intramedullary ring-shaped structure in the cervical cord, an AIDS-associated vasculopathy and symmetric calcifications in the basal ganglia. The spectrum of neuroradiological findings in paediatric AIDS patients differs from that in adults. Knowledge of these age-specific findings is important because the number of HIV-infected children is rising.

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Year:  1994        PMID: 8054542     DOI: 10.1055/s-2008-1032502

Source DB:  PubMed          Journal:  Rofo        ISSN: 1438-9010


  3 in total

1.  Correlating brain volume and callosal thickness with clinical and laboratory indicators of disease severity in children with HIV-related brain disease.

Authors:  Savvas Andronikou; Christelle Ackermann; Barbara Laughton; Mark Cotton; Nicollette Tomazos; Bruce Spottiswoode; Katya Mauff; John M Pettifor
Journal:  Childs Nerv Syst       Date:  2014-05-23       Impact factor: 1.475

2.  Corpus callosum thickness on mid-sagittal MRI as a marker of brain volume: a pilot study in children with HIV-related brain disease and controls.

Authors:  Savvas Andronikou; Christelle Ackermann; Barbara Laughton; Mark Cotton; Nicollette Tomazos; Bruce Spottiswoode; Katya Mauff; John M Pettifor
Journal:  Pediatr Radiol       Date:  2015-01-27

3.  White matter signal abnormalities in children with suspected HIV-related neurologic disease on early combination antiretroviral therapy.

Authors:  Christelle Ackermann; Savvas Andronikou; Barbara Laughton; Martin Kidd; Els Dobbels; Steve Innes; Ronald van Toorn; Mark Cotton
Journal:  Pediatr Infect Dis J       Date:  2014-08       Impact factor: 2.129

  3 in total

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