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Literature DB >> 8054511

The role of the extracellular matrix in tumor cell metastasis.

M L Stracke¹, J Murata, S Aznavoorian, L A Liotta.

Abstract

The extracellular matrix is a macromolecular network that surrounds cells and makes up a significant portion of their microenvironment. During the processes of invasion and metastasis, tumor cells encounter interstitial stroma and basement membranes many times. In fact, tumor cell response to extracellular matrix components appears to be a major determinant of metastatic potential.

Entities: Disease

Mesh：

Year: 1994 PMID： 8054511

Source DB: PubMed Journal: In Vivo ISSN： 0258-851X Impact factor: 2.155

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Cited

11 in total

1. Identification and characterization of motility stimulating factor secreted from pancreatic cancer cells: role in tumor invasion and metastasis.

Authors: Y Sakurai; T Sawada; Y S Chung; Y Funae; M Sowa
Journal: Clin Exp Metastasis Date: 1997-05 Impact factor: 5.150

2. Genistein-stimulated adherence of prostate cancer cells is associated with the binding of focal adhesion kinase to beta-1-integrin.

Authors: R Bergan; E Kyle; P Nguyen; J Trepel; C Ingui; L Neckers
Journal: Clin Exp Metastasis Date: 1996-09 Impact factor: 5.150

3. [Ca2+]i as a potential downregulator of alpha2beta1-integrin-mediated A2058 tumor cell migration to type IV collagen.

Authors: L Hodgson; C Dong
Journal: Am J Physiol Cell Physiol Date: 2001-07 Impact factor: 4.249

Review 4. Metastasis suppressor genes at the interface between the environment and tumor cell growth.

Authors: Douglas R Hurst; Danny R Welch
Journal: Int Rev Cell Mol Biol Date: 2011 Impact factor: 6.813

5. Basement membrane proteins play an active role in the invasive process of human hepatocellular carcinoma cells with high metastasis potential.

Authors: Bo Tian; Yan Li; Xue-Ning Ji; Jie Chen; Qiong Xue; Sheng-Long Ye; Yin-Kun Liu; Zhao-You Tang
Journal: J Cancer Res Clin Oncol Date: 2004-10-12 Impact factor: 4.553

The role of the extracellular matrix in tumor cell metastasis.

1. Identification and characterization of motility stimulating factor secreted from pancreatic cancer cells: role in tumor invasion and metastasis.

2. Genistein-stimulated adherence of prostate cancer cells is associated with the binding of focal adhesion kinase to beta-1-integrin.

3. [Ca2+]i as a potential downregulator of alpha2beta1-integrin-mediated A2058 tumor cell migration to type IV collagen.

Review 4. Metastasis suppressor genes at the interface between the environment and tumor cell growth.

5. Basement membrane proteins play an active role in the invasive process of human hepatocellular carcinoma cells with high metastasis potential.

6. In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals.

7. Melanoma cell migration to type IV collagen requires activation of NF-kappaB.

8. Distribution of integrin cell adhesion molecules in endometrial cancer.

9. Tissue transglutaminase-induced alterations in extracellular matrix inhibit tumor invasion.

10. COL11A1 in FAP polyps and in sporadic colorectal tumors.