Literature DB >> 805436

Excessive thyrotropin concentrations in the circulation of the spontaneously hypertensive rat.

S C Werner, W M Manger, I Radichevich, M Wolff, I von Estorff.   

Abstract

Thyroid funct-on in SHR was compared to that of inbred normotensive Wistar rats from Kyoto, and random bred Wistar rats from the United States. A marked increase in circulating thyrotropin concentration was found in SHR compared to controls. Serum thyroxine and T3 concentrations relative to controls, however, were variable and the concentrations in male and female SHR relative to Kyoto controls did not correspond with each other. No ready explanation for the circulating excess of thyrotropin, with mimimal increase in T4 and T3 concentrations, is available.

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Year:  1975        PMID: 805436     DOI: 10.3181/00379727-148-38679

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  3 in total

1.  Skeletal muscle adaptation to physical training and beta-adrenergic blockade in spontaneously hypertensive rats.

Authors:  R J Favier; F Ghaemmaghami; B Sempore; D Desplanches; M H Mayet; J Frutoso; C Gharib; R Flandrois
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1989

2.  Studies on the mechanism of the enhanced cold-induced TSH secretion in spontaneously hypertensive rats.

Authors:  J Mattila; P T Männistö; R K Tuominen
Journal:  Experientia       Date:  1983-04-15

3.  Hypothalamus-adenohypohysis-thyroid axis in spontaneously hypertensive rats (SHR).

Authors:  P T Männistö; J Mattila
Journal:  Experientia       Date:  1981
  3 in total

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