| Literature DB >> 805431 |
J P Van Miller, I C Hsu, J R Allen.
Abstract
Distribution and metabolism of an isomeric polychlorinated biphenyl were determined in rats. Over 70% of a single dose of 3H-2,5,2',5'-tetrachlorobiphenyl was excreted in the feces and another 13% in the urine during a 14-day period. Adipose tissue, blood, skin, and liver were found to contain low levels of the compound. Over 90% of the excreted tritiated compound was found to be metabolized, the major metabolite being identified as 3-OH-2,5,2',5'-tetrachlorobiphenyl. All of the unmetabolized 2,5,2',5'-tetrachlorobiphenyl was eliminated by the alimentary route.Entities:
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Year: 1975 PMID： 805431 DOI： 10.3181/00379727-148-38610
Source DB: PubMed Journal: Proc Soc Exp Biol Med ISSN： 0037-9727