| Literature DB >> 8053415 |
Abstract
This article provides an overview of different brain insults leading to induction of astroglial NGF expression. It discusses mechanisms of induction of astroglial NGF in a damaged brain and a possible role of its expression in pathophysiology of Alzheimer's disease. It emphasizes that the pharmacological manipulation of astroglial production of NGF may serve as a possible therapeutic strategy to ameliorate the pathological changes occurring after brain damage.Entities:
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Year: 1994 PMID: 8053415
Source DB: PubMed Journal: Acta Neurobiol Exp (Wars) ISSN: 0065-1400 Impact factor: 1.579