Literature DB >> 8053016

Natural products as drugs.

J D Phillipson1.   

Abstract

Higher plants, many of which are threatened with extinction, are used as sources of pharmaceuticals and as ingredients of traditional medicines and are of value in new drug discovery. Artemisinin, taxol and camptothecin are examples of natural products which are undergoing clinical and commercial development. Several natural products isolated from plants used in traditional medicine have potent antiplasmodial action in vitro and represent potential sources of new antimalarial drugs. Plant biotechnology offers the possibility of improved production methods of cultivated medicinal plants as well as alternative approaches to the production of natural products for the preparation of pharmaceuticals.

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Year:  1994        PMID: 8053016     DOI: 10.1016/0035-9203(94)90464-2

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  5 in total

Review 1.  The role of plant-derived drugs and herbal medicines in healthcare.

Authors:  P A De Smet
Journal:  Drugs       Date:  1997-12       Impact factor: 9.546

2.  Traditional management of tuberculosis in Ogun State of Nigeria: the practice and ethnobotanical survey.

Authors:  Omonike O Ogbole; Edith O Ajaiyeoba
Journal:  Afr J Tradit Complement Altern Med       Date:  2009-10-15

3.  Anti-plasmodial effects of Azadirachta indica in experimental cerebral malaria: Apoptosis of cerebellar Purkinje cells of mice as a marker.

Authors:  Mohammed Farahna; Selma Bedri; Sami Khalid; Mustafa Idris; C Radhakrishna Pillai; Eltahir A Khalil
Journal:  N Am J Med Sci       Date:  2010-11

4.  Antimicrobial activity and probable mechanisms of action of medicinal plants of Kenya: Withania somnifera, Warbugia ugandensis, Prunus africana and Plectrunthus barbatus.

Authors:  Peter G Mwitari; Peter A Ayeka; Joyce Ondicho; Esther N Matu; Christine C Bii
Journal:  PLoS One       Date:  2013-06-13       Impact factor: 3.240

Review 5.  Medicinal plants: a source of anti-parasitic secondary metabolites.

Authors:  Michael Wink
Journal:  Molecules       Date:  2012-10-31       Impact factor: 4.411

  5 in total

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