Literature DB >> 8050515

Properties of the transient potassium currents in cerebellar granule cells.

O Zegarra-Moran1, O Moran.   

Abstract

Macroscopic potassium currents were studied in cell-attached and inside-out patches from rat cerebellar granule cells. They were related with transient IA type potassium channels. Currents activated rapidly at potentials higher than -40 mV and did not inactivate completely. The magnitude of the current diminished when the membrane patches were excised. No differences in the activation and inactivation properties were found between patches in the integral cells and cell free membrane patches. A biophysical description of the currents is presented.

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Year:  1994        PMID： 8050515     DOI： 10.1007/bf00228417

Source DB:  PubMed          Journal:  Exp Brain Res        ISSN： 0014-4819            Impact factor:   1.972


  25 in total

1.  A novel K+ channel with unique localizations in mammalian brain: molecular cloning and characterization.

Authors:  P M Hwang; C E Glatt; D S Bredt; G Yellen; S H Snyder
Journal:  Neuron       Date:  1992-03       Impact factor: 17.173

2.  Development of voltage-dependent ionic currents in rat cerebellar granule cells grown in primary culture.

Authors:  Z Galdzicki; F Lin; O Moran; A Novelli; G Puia; M Sciancalepore
Journal:  Int J Neurosci       Date:  1991 Jan-Feb       Impact factor: 2.292

3.  Two types of inactivation in Shaker K+ channels: effects of alterations in the carboxy-terminal region.

Authors:  T Hoshi; W N Zagotta; R W Aldrich
Journal:  Neuron       Date:  1991-10       Impact factor: 17.173

4.  Single-channel and whole-cell currents in rat cerebellar granule cells.

Authors:  T Jalonen; S Johansson; I Holopainen; S S Oja; P Arhem
Journal:  Brain Res       Date:  1990-12-03       Impact factor: 3.252

5.  K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.

Authors:  A Wei; M Covarrubias; A Butler; K Baker; M Pak; L Salkoff
Journal:  Science       Date:  1990-05-04       Impact factor: 47.728

6.  Gating of single Shaker potassium channels in Drosophila muscle and in Xenopus oocytes injected with Shaker mRNA.

Authors:  W N Zagotta; T Hoshi; R W Aldrich
Journal:  Proc Natl Acad Sci U S A       Date:  1989-09       Impact factor: 11.205

7.  Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes.

Authors:  E Y Isacoff; Y N Jan; L Y Jan
Journal:  Nature       Date:  1990-06-07       Impact factor: 49.962

8.  Heteromultimeric K+ channels in terminal and juxtaparanodal regions of neurons.

Authors:  H Wang; D D Kunkel; T M Martin; P A Schwartzkroin; B L Tempel
Journal:  Nature       Date:  1993-09-02       Impact factor: 49.962

9.  Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.

Authors:  O P Hamill; A Marty; E Neher; B Sakmann; F J Sigworth
Journal:  Pflugers Arch       Date:  1981-08       Impact factor: 3.657

10.  Voltage-activated calcium channels that must be phosphorylated to respond to membrane depolarization.

Authors:  D Armstrong; R Eckert
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205
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  5 in total

1.  Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice.

Authors:  P A Slesinger; M Stoffel; Y N Jan; L Y Jan
Journal:  Proc Natl Acad Sci U S A       Date:  1997-10-28       Impact factor: 11.205

2.  The weaver mutation of GIRK2 results in a loss of inwardly rectifying K+ current in cerebellar granule cells.

Authors:  D J Surmeier; P G Mermelstein; D Goldowitz
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-01       Impact factor: 11.205

3.  Incorporation of DPP6a and DPP6K variants in ternary Kv4 channel complex reconstitutes properties of A-type K current in rat cerebellar granule cells.

Authors:  Henry H Jerng; Paul J Pfaffinger
Journal:  PLoS One       Date:  2012-06-04       Impact factor: 3.240

Review 4.  What are the roles of the many different types of potassium channel expressed in cerebellar granule cells?

Authors:  Alistair Mathie; Catherine E Clarke; Kishani M Ranatunga; Emma L Veale
Journal:  Cerebellum       Date:  2003       Impact factor: 3.847

Review 5.  Modulatory mechanisms and multiple functions of somatodendritic A-type K (+) channel auxiliary subunits.

Authors:  Henry H Jerng; Paul J Pfaffinger
Journal:  Front Cell Neurosci       Date:  2014-03-27       Impact factor: 5.505
  5 in total

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