Literature DB >> 8048203

Laboratory variables of bladder autoaugmentation in an animal model.

H W Johnson1, M K Nigro, L Stothers, H Tearle, W J Arnold.   

Abstract

OBJECTIVES: Evaluations of the functional, radiologic, and pathologic outcomes of autoaugmentation by two surgical techniques (vesicomyectomy versus vesicomyotomy) were compared. Autoaugmentation or vesicomyotomy is being increasingly considered as a simplified method of bladder augmentation in the hypertonic decreased-capacity bladder.
METHODS: In a series of 35 laboratory sessions, creation of an animal model approximating the small-capacity hypertonic bladder was achieved. Sixteen vesicomyotomies and 16 vesicomyectomies were performed on the 32 stabilized one-third reduced bladders. Three stabilized one-third reduced bladders were used as controls.
RESULTS: Radiologic studies show a large diverticulum. A 17.2% net increase in surface area was achieved, compared with the reduced bladder, at the time of pathologic examination. Functional capacity was increased by 43.5% on urodynamic studies, and leak point pressure was decreased by 48.1%. Histologic and morphometric examinations of the autoaugmentation area showed a few muscle fibers with serosal deposition of collagen. There was less muscle ingrowth at the periphery of the autoaugmentation site utilizing vesicomyectomy.
CONCLUSIONS: There was no statistical difference between vesicomyotomy and vesicomyectomy with respect to radiologic, pathologic, or urodynamic outcome.

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Mesh:

Year:  1994        PMID: 8048203     DOI: 10.1016/s0090-4295(94)80145-2

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  3 in total

1.  Long-term follow-up and evaluation of autoaugmentation cystoplasty (detrusorotomy) in an animal model.

Authors:  C Taneli; A Genç
Journal:  Int Urol Nephrol       Date:  1999       Impact factor: 2.370

Review 2.  The evolution of bladder augmentation: from creating a reservoir to reconstituting an organ.

Authors:  Roman Jednak
Journal:  Front Pediatr       Date:  2014-02-10       Impact factor: 3.418

3.  Comparison of bladder autoaugmentation by transurethral vesicomyotomy and hydrodistention for ketamine cystitis.

Authors:  Shuo Tan; Xuan Zhu; Zhihuan Zheng; Long Zheng; Ye Kang; Zhengyan Tang
Journal:  Transl Androl Urol       Date:  2021-06
  3 in total

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