Literature DB >> 804745

[Influence of autolysis on the immunohistology of tissue-bound immunglobulins in the kidney (author's transl)].

H P Seelig, R Seelig, M Drescher.   

Abstract

The influence of autolysis on the immunhistological detectability and the immunological properties of tissue-bound basement membrane antibodies were investigated in the rat kidney. The immunhistological demonstration of antibodies was not affected up to 3 days post mortem. The disturbing autofluorescence of the autolytic tissue can be avoided by using peroxydase labeled antibodies. Basement-membrane antibodies that were eluted from the kidneys after an autolysis period of 2 days showed a homogenous linear deposition in kidney basement membrane after reinjection into normal rats. Their antibody properties were not affected.

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Year:  1975        PMID： 804745     DOI： 10.1007/BF00432386

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histol        ISSN： 0340-1227


  6 in total

1.  IMMUNOLOGICAL FEATURES IN THE CONGENITAL NEPHROTIC SYNDROME: A CLINICAL AND EXPERIMENTAL STUDY.

Authors:  K KOUVALAINEN
Journal:  Ann Paediatr Fenn       Date:  1963

2.  [Isolation of human serum group-specific protein (Gc) by immunoadsorption (author's transl)].

Authors:  H Jungfer; R Tremper
Journal:  Z Immunitatsforsch Exp Klin Immunol       Date:  1972-01

3.  Variable patterns of immunoglobulin and complement deposition in the kidneys of patients with systemic lupus erythematosus.

Authors:  D Koffler; V Agnello; R I Carr; H G Kunkel
Journal:  Am J Pathol       Date:  1969-09       Impact factor: 4.307

4.  Coupling of enzymes to proteins with glutaraldehyde. Use of the conjugates for the detection of antigens and antibodies.

Authors:  S Avrameas
Journal:  Immunochemistry       Date:  1969-01

5.  The nephrotic syndrome of infancy: clinical, morphologic, and immunologic studies of four infants.

Authors:  J R Hoyer; A F Michael; R A Good; R L Vernier
Journal:  Pediatrics       Date:  1967-08       Impact factor: 7.124

6.  Experimental hemorrhagic pneumonitis produced by heterologous anti-lung antibody.

Authors:  W F Willoughby; F J Dixon
Journal:  J Immunol       Date:  1970-01       Impact factor: 5.422
  6 in total
  2 in total

1.  Complement-mediated acinar cell necroses in pancreatitis induced by basement membrane antibodies.

Authors:  R Seelig; H P Seelig
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1976-08-19

2.  The serum complement system--a mediator of acute pancreatitis.

Authors:  R Seelig; V Ehemann; C Tschahargane; H P Seelig
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1975
  2 in total

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