Literature DB >> 804435

Role of antibodies to galactocerebroside in experimental allergic encephalomyelitis.

R A Hughes, S Leibowitz.   

Abstract

The possible role of antibodies to galactocerebroside was investigated in AS rats with experimental allergic encephalomyelitis (EAE) induced by guinea-pig spinal cord. Passive immunization with rat or rabbit antiserum to galactocerebroside did not protect rats from EAE. Active immunization with galactocerebroside before the encephalitogenic challenge produced antibody to galactocerebroside but also failed to protect rats from EAE. These experiments did not support previous suggestions that antibodies to galactocerebroside are protective.

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Year:  1975        PMID: 804435      PMCID: PMC1445798     

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  8 in total

1.  Specificity of encephalitogen-induced inhibition of experimental "allergic" encephalomyelitis in the guinea pig.

Authors:  C M SHAW; E C ALVORD; W J FAHLBERG; M W KIES
Journal:  J Immunol       Date:  1962-07       Impact factor: 5.422

2.  The effect of prior injections of tissue antiserums on the survival of cancer homoiografts in mice.

Authors:  N KALISS; N MOLOMUT
Journal:  Cancer Res       Date:  1952-02       Impact factor: 12.701

3.  Immunopathologic response in guinea pigs sensitized with peripheral nervous system myelin.

Authors:  S W Brostoff; H M Wisniewski; S Greenfield; P Morell; E H Eylar
Journal:  Brain Res       Date:  1973-08-30       Impact factor: 3.252

4.  Immunologic unresponsiveness, immunity and enhancement in experimental allergic encephalomyelitis.

Authors:  S B Salvin; H L Liauw
Journal:  J Immunol       Date:  1968-07       Impact factor: 5.422

5.  The susceptibility of rat strains to experimental allergic encephalomyelitis.

Authors:  R A Hughes; J Stedronska
Journal:  Immunology       Date:  1973-05       Impact factor: 7.397

6.  Protection of rats from experimental allergic encephalomyelitis with antiserum to guinea-pig spinal cord.

Authors:  R A Hughes
Journal:  Immunology       Date:  1974-04       Impact factor: 7.397

7.  Dissociation of antibody production from disease suppression in the inhibition of allergic encephalomyelitis by myelin basic protein.

Authors:  R P Lisak; G A Falk; R G Heinze; M W Kies; E C Alvord
Journal:  J Immunol       Date:  1970-06       Impact factor: 5.422

8.  Suppression of allergic encephalomyelitis in rats by means of antibrain serum.

Authors:  P Y PATERSON; S M HARWIN
Journal:  J Exp Med       Date:  1963-05-01       Impact factor: 14.307

  8 in total
  2 in total

1.  Suppressor T cells prevent experimental autoimmune encephalomyelitis in mice.

Authors:  C C Bernard
Journal:  Clin Exp Immunol       Date:  1977-07       Impact factor: 4.330

2.  Immune response to myelin basic protein in multiple sclerosis.

Authors:  R A Hughes; I Gray; R Clifford-Jones; M Stern
Journal:  Proc R Soc Med       Date:  1977-12
  2 in total

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