| Literature DB >> 8044290 |
J Sochor1, J Klimes, M Zahradnícek, J Sedlácek.
Abstract
A precise, accurate, reproducible one-step method for the high-performance chromatographic determination of ibuprofen in whole blood is described. Samples were, after haemolysis, prepared by solid-phase extraction. Analyses were performed using reversed-phase chromatography on a Separon SGX C18 column with a mobile phase of methanol-water (pH 3) and ultraviolet detection at 222 nm. The method was used for pharmacokinetic studies in rabbits.Entities:
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Year: 1994 PMID： 8044290 DOI： 10.1016/0378-4347(94)00018-2
Source DB: PubMed Journal: J Chromatogr B Biomed Appl ISSN： 1572-6495