| Literature DB >> 8043300 |
Y Okuda1, M Ezure, K Tsukahara, T Sawada, M Mizutani, T Katori, C Bannai, K Yamashita.
Abstract
Eicosapentaenoic acid (EPA) caused elevations of intracellular free Ca2+ concentration ([Ca2+]i) measured by fura-2 fluorescence in cultured human endothelial cells. The EPA-induced increase in [Ca2+]i could still be observed when either cyclooxygenase or lipoxygenase inhibitors were added. These results suggest that EPA itself rather than its metabolites has direct effects on intracellular Ca2+ mobilization, causing the elevation of [Ca2+]i.Entities:
Mesh：
Substances：
Year: 1994 PMID： 8043300 DOI： 10.1006/bmmb.1994.1021
Source DB: PubMed Journal: Biochem Med Metab Biol ISSN： 0885-4505