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Literature DB >> 8039831

The genes encoding NK cell granule serine proteases, human tryptase-2 (TRYP2) and human granzyme A (HFSP), both map to chromosome 5q11-q12 and define a new locus for cytotoxic lymphocyte granule tryptases.

E Baker¹, T J Sayers, G R Sutherland, M J Smyth.

Abstract

Entities: Gene Species

Mesh：

Substances：

Year: 1994 PMID： 8039831 DOI： 10.1007/bf00167085

Source DB: PubMed Journal: Immunogenetics ISSN： 0093-7711 Impact factor: 2.846

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13 in total

1. Reassessment of two apparent deletions of chromosome 16p to an ins(11;16) and a t(1;16) by chromosome painting.

Authors: D F Callen; E Baker; H J Eyre; J E Chernos; J A Bell; G R Sutherland
Journal: Ann Genet Date: 1990

Review 2. Perforin-mediated target cell lysis by cytolytic T lymphocytes.

Authors: J Tschopp; M Nabholz
Journal: Annu Rev Immunol Date: 1990 Impact factor: 28.527

Review 3. Internal disintegration model of cytotoxic lymphocyte-induced target damage.

Authors: J H Russell
Journal: Immunol Rev Date: 1983 Impact factor: 12.988

4. Proximity of the CTLA-1 serine esterase and Tcr alpha loci in mouse and man.

Authors: K Harper; M G Mattéi; D Simon; M Suzan; J L Guénet; P Haddad; M Sasportes; P Golstein
Journal: Immunogenetics Date: 1988 Impact factor: 2.846

5. Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A.

Authors: J W Shiver; L Su; P A Henkart
Journal: Cell Date: 1992-10-16 Impact factor: 41.582

6. A cluster of hematopoietic serine protease genes is found on the same chromosomal band as the human alpha/delta T-cell receptor locus.

Authors: R D Hanson; P A Hohn; N C Popescu; T J Ley
Journal: Proc Natl Acad Sci U S A Date: 1990-02 Impact factor: 11.205

7. Purification and cloning of a novel serine protease, RNK-Tryp-2, from the granules of a rat NK cell leukemia.

Authors: T J Sayers; T A Wiltrout; M J Smyth; K S Ottaway; A M Pilaro; R Sowder; L E Henderson; H Sprenger; A R Lloyd
Journal: J Immunol Date: 1994-03-01 Impact factor: 5.422

8. Purified perforin induces target cell lysis but not DNA fragmentation.

Authors: R C Duke; P M Persechini; S Chang; C C Liu; J J Cohen; J D Young
Journal: J Exp Med Date: 1989-10-01 Impact factor: 14.307

9. Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions.

Authors: L Shi; C M Kam; J C Powers; R Aebersold; A H Greenberg
Journal: J Exp Med Date: 1992-12-01 Impact factor: 14.307

The genes encoding NK cell granule serine proteases, human tryptase-2 (TRYP2) and human granzyme A (HFSP), both map to chromosome 5q11-q12 and define a new locus for cytotoxic lymphocyte granule tryptases.

1. Reassessment of two apparent deletions of chromosome 16p to an ins(11;16) and a t(1;16) by chromosome painting.

Review 2. Perforin-mediated target cell lysis by cytolytic T lymphocytes.

Review 3. Internal disintegration model of cytotoxic lymphocyte-induced target damage.

4. Proximity of the CTLA-1 serine esterase and Tcr alpha loci in mouse and man.

5. Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A.

6. A cluster of hematopoietic serine protease genes is found on the same chromosomal band as the human alpha/delta T-cell receptor locus.

7. Purification and cloning of a novel serine protease, RNK-Tryp-2, from the granules of a rat NK cell leukemia.

8. Purified perforin induces target cell lysis but not DNA fragmentation.

9. Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions.

10. A natural killer cell granule protein that induces DNA fragmentation and apoptosis.

1. Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells.

2. The natural killer cell serine protease gene Lmet1 maps to mouse chromosome 10.

Review 3. Granzymes: a family of lymphocyte granule serine proteases.

Review 4. Granzymes: The Molecular Executors of Immune-Mediated Cytotoxicity.

5. Molecular subsets in the gene expression signatures of scleroderma skin.