Literature DB >> 803739

Experimental polymer storage disease in rabbits. An approach to the histogenesis of sphingolipidoses.

K Miyasaki.   

Abstract

Water-soluble polymer compound, polyvinyl alcohol(PVA), and water-insoluble polymer compounds, polyvinyl acetate (PVAc) and polystylol (PS), were administered in 297 rabbits. When high polymerized PVA, PVAc or PS were continuously injected intravenously for a long period of time, lesions resembled to those of Gaucher and Niemann-Pick diseases were developed. From these experimental results, pathological development of various sphingolipidoses found in the human body was discussed and pathological findings were analysed polymer-chemically from the chemical properties of the substances stored.

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Year:  1975        PMID： 803739     DOI： 10.1007/BF00471182

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histol        ISSN： 0340-1227


  28 in total

1.  GENERALIZED GANGLIOSIDOSIS: ANOTHER INBORN ERROR OF GANGLIOSIDE METABOLISM?

Authors:  J S O'BRIEN; M B STERN; B H LANDING; J K O'BRIEN; G N DONNELL
Journal:  Am J Dis Child       Date:  1965-04

2.  The genetic mucolipidoses. Diagnosis and differential diagnosis.

Authors:  J W Spranger; H R Wiedemann
Journal:  Humangenetik       Date:  1970

3.  Lipomucopolysaccharidosis--a second look.

Authors:  J Spranger; H R Wiedemann
Journal:  Lancet       Date:  1969-08-02       Impact factor: 79.321

4.  Glycosphingolipidosis. Accumulation of ceramide trihexoside and globoside.

Authors:  K Miyasaki; K Saito
Journal:  Arch Pathol       Date:  1973-12

5.  Ultrastructural study of experimental globoid cells.

Authors:  K Suzuki
Journal:  Lab Invest       Date:  1970-12       Impact factor: 5.662

6.  Deficiency of sphingomyelin-cleaving enzyme activity in tissue cultures derived from patients with Niemann-Pick disease.

Authors:  H R Sloan; B W Uhlendorf; J N Kanfer; R O Brady; D S Fredrickson
Journal:  Biochem Biophys Res Commun       Date:  1969-03-10       Impact factor: 3.575

7.  Lactosyl ceramidosis: catabolic enzyme defect of glycosphingolipid metabolism.

Authors:  G Dawson; A O Stein
Journal:  Science       Date:  1970-10-30       Impact factor: 47.728

8.  The metabolism of ceramide trihexosides. I. Purification and properties of an enzyme that cleaves the terminal galactose molecule of galactosylgalactosylglucosylceramide.

Authors:  R O Brady; A E Gal; R M Bradley; E Mårtensson
Journal:  J Biol Chem       Date:  1967-03-10       Impact factor: 5.157

9.  Fabry's disease: alpha-galactosidase deficiency.

Authors:  J A Kint
Journal:  Science       Date:  1970-02-27       Impact factor: 47.728

10.  THE METABOLISM OF GLUCOCEREBROSIDES. I. PURIFICATION AND PROPERTIES OF A GLUCOCEREBROSIDE-CLEAVING ENZYME FROM SPLEEN TISSUE.

Authors:  R O BRADY; J KANFER; D SHAPIRO
Journal:  J Biol Chem       Date:  1965-01       Impact factor: 5.157
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  3 in total

1.  Fully degradable hydrophilic polyals for protein modification.

Authors:  Alexander Yurkovetskiy; Sungwoon Choi; Alexander Hiller; Mao Yin; Catherine McCusker; Sakina Syed; Alan J Fischman; Mikhail I Papisov
Journal:  Biomacromolecules       Date:  2005 Sep-Oct       Impact factor: 6.988

2.  Effect of liposome characteristics and dose on the pharmacokinetics of liposomes coated with poly(amino acid)s.

Authors:  Birgit Romberg; Christien Oussoren; Cor J Snel; Wim E Hennink; Gert Storm
Journal:  Pharm Res       Date:  2007-08-03       Impact factor: 4.200

3.  Surface engineering of liposomes for stealth behavior.

Authors:  Okhil K Nag; Vibhudutta Awasthi
Journal:  Pharmaceutics       Date:  2013-10-25       Impact factor: 6.321
  3 in total

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