Literature DB >> 8037339

Pain in children and adolescents with sickle cell anemia: a prospective study utilizing self-reporting.

K A Sporrer1, S M Jackson, S Agner, J Laver, M R Abboud.   

Abstract

PURPOSE: The purpose of this study was to characterize pain reporting among children with sickle cell anemia (SCA) experiencing painful vaso-occlusive crises. These patients were managed according to a protocol based on self-reports of pain. PATIENTS AND METHODS: Seventeen children (3-18 years) with SCA (Hb SS) who were admitted for painful crisis were asked to report their pain according to a rating scale of 0-5. These pain scores were analyzed according to the Mann-Whitney method to determine differences in pain reporting among young children (3-12 years) and adolescents (13-18 years). The Kruskal-Wallis method was utilized to determine relationships between the number of painful body sites, reported pain scores, and length of hospital stay.
RESULTS: Children (3-12 years) reported significantly less severe pain than adolescents (13-18 years) (p < 0.01). The severity of pain reported was not related to the number of painful sites. However, the length of stay was significantly longer in patients with greater numbers of painful sites (p < 0.05). Patients who reported pain scores of > 2 at 24 h had significantly longer periods of hospitalization.
CONCLUSION: A protocol based upon self-reports of pain was successfully utilized to provide analgesia during painful crises. There were characteristic differences between young children and adolescents in self-reporting of pain. Pain scores may be helpful in predicting length of hospitalization for painful crises.

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Mesh:

Year:  1994        PMID: 8037339     DOI: 10.1097/00043426-199408000-00006

Source DB:  PubMed          Journal:  Am J Pediatr Hematol Oncol        ISSN: 0192-8562


  5 in total

1.  Pain site frequency and location in sickle cell disease: the PiSCES project.

Authors:  Donna K McClish; Wally R Smith; Bassam A Dahman; James L Levenson; John D Roberts; Lynne T Penberthy; Imoigele P Aisiku; Susan D Roseff; Viktor E Bovbjerg
Journal:  Pain       Date:  2009-07-23       Impact factor: 6.961

2.  Quantification of pain in sickle mice using facial expressions and body measurements.

Authors:  Aditya Mittal; Mihir Gupta; Yann Lamarre; Balkrishna Jahagirdar; Kalpna Gupta
Journal:  Blood Cells Mol Dis       Date:  2015-12-14       Impact factor: 3.039

3.  Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids.

Authors:  Divyanshoo R Kohli; Yunfang Li; Sergey G Khasabov; Pankaj Gupta; Lois J Kehl; Marna E Ericson; Julia Nguyen; Vinita Gupta; Robert P Hebbel; Donald A Simone; Kalpna Gupta
Journal:  Blood       Date:  2010-03-19       Impact factor: 22.113

4.  Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia.

Authors:  Jianxun Lei; Barbara Benson; Huy Tran; Solomon F Ofori-Acquah; Kalpna Gupta
Journal:  PLoS One       Date:  2016-08-05       Impact factor: 3.240

5.  Guidelines on neonatal screening and painful vaso-occlusive crisis in sickle cell disease: Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular: Project guidelines: Associação Médica Brasileira - 2016.

Authors:  Josefina Aparecida Pellegrini Braga; Mônica Pinheiro de Almeida Veríssimo; Sara Teresinha Olalla Saad; Rodolfo Delfini Cançado; Sandra Regina Loggetto
Journal:  Rev Bras Hematol Hemoter       Date:  2016-04-08
  5 in total

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