Literature DB >> 8035417

Retro-binding tripeptide thrombin active-site inhibitors: discovery, synthesis, and molecular modeling.

E J Iwanowicz1, W F Lau, J Lin, D G Roberts, S M Seiler.   

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Year:  1994        PMID： 8035417     DOI： 10.1021/jm00040a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  2 in total

1.  Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex.

Authors:  G De Simone; A Lombardi; S Galdiero; F Nastri; R Della Morte; N Staiano; C Pedone; M Bolognesi; V Pavone
Journal:  Protein Sci       Date:  1998-02       Impact factor: 6.725

2.  The crystal structures of human alpha-thrombin complexed with active site-directed diamino benzo[b]thiophene derivatives: a binding mode for a structurally novel class of inhibitors.

Authors:  N Y Chirgadze; D J Sall; S L Briggs; D K Clawson; M Zhang; G F Smith; R W Schevitz
Journal:  Protein Sci       Date:  2000-01       Impact factor: 6.725
  2 in total

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