Literature DB >> 8034998

Lyme borreliosis associated with complete flaccid paraplegia.

R Salonen1, J O Rinne, P Halonen, A Puusa, R Marttila, M K Viljanen.   

Abstract

We report the case of a patient with concomitant Lyme borreliosis and acute paraplegia. The paraplegia was complete, flaccid and of upper motor neurone type. The diagnosis of borreliosis was based on the detection of large amounts of IgM and IgG borrelia antibodies in the acute phase serum and on the complete disappearance of IgM antibody during the review period. IgG borrelia antibodies were also detected in the CSF, but leakage of antibodies from the blood to the intrathecal space could not be ruled out. Lymphocytosis and increased total protein concentration in the CSF were signs compatible with neuroborreliosis. Ceftriaxone therapy effected dramatic recovery of the patient. This case suggests that borreliosis should be considered a possible cause of acute flaccid paraplegia.

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Year:  1994        PMID: 8034998     DOI: 10.1016/s0163-4453(94)95660-x

Source DB:  PubMed          Journal:  J Infect        ISSN: 0163-4453            Impact factor:   6.072


  2 in total

1.  Acute Flaccid Paralysis: The New, The Old, and The Preventable.

Authors:  N Macesic; V Hall; A Mahony; L Hueston; G Ng; R Macdonell; A Hughes; G Fitt; M L Grayson
Journal:  Open Forum Infect Dis       Date:  2015-12-09       Impact factor: 3.835

Review 2.  Neuroinflammation as a Common Feature of Neurodegenerative Disorders.

Authors:  Leonardo Guzman-Martinez; Ricardo B Maccioni; Víctor Andrade; Leonardo Patricio Navarrete; María Gabriela Pastor; Nicolas Ramos-Escobar
Journal:  Front Pharmacol       Date:  2019-09-12       Impact factor: 5.810

  2 in total

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