| Literature DB >> 8034807 |
T A Maurer1, H S Zackheim, L Tuffanelli, T G Berger.
Abstract
The use of methotrexate (MTX) has been contraindicated for treatment of severe psoriasis in HIV infection on the basis of six previously reported cases in which MTX appeared to potentiate opportunistic infections and accelerate HIV disease. We describe three HIV-infected patients who were given MTX for severe psoriatic arthritis. In two patients opportunistic infections did not develop. On the basis of survival data, it is not clear that use of MTX adversely affected the natural course of their HIV disease.Entities:
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Year: 1994 PMID： 8034807 DOI： 10.1016/s0190-9622(94)70175-x
Source DB: PubMed Journal: J Am Acad Dermatol ISSN： 0190-9622 Impact factor: 11.527