Literature DB >> 8034760

Evidence for genetic contamination of inbred buffalo rats (RT-1b) obtained from a commercial vendor.

R E Jones1, A Weinberg, D Bourdette.   

Abstract

Inbred Buffalo rats (RT-1b) have been used in studies of experimental autoimmune encephalomyelitis and autoimmune thyroiditis. Since our studies, and those of others, have relied on the genetic purity of inbred Buffalo rats, we chose to test these animals for expression of strain-dependent, allotype-specific variants of CD45 (leukocyte common antigen, LCA) using the monoclonal antibodies RT7.1 and RT7.2. The goal of this study was to confirm the genetic purity and to verify the inbred status of Buffalo rats obtained from a commercial source.

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Year:  1994        PMID: 8034760     DOI: 10.1016/0165-5728(94)90115-5

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN: 0165-5728            Impact factor:   3.478


  2 in total

1.  DA rats from two colonies differ genetically and in their arthritis susceptibility.

Authors:  Carola Rintisch; Rikard Holmdahl
Journal:  Mamm Genome       Date:  2008-07-31       Impact factor: 2.957

2.  Development of mammary cancer in γ-irradiated F1 hybrids of susceptible Sprague-Dawley and resistant Copenhagen rats, with copy-number losses that pinpoint potential tumor suppressors.

Authors:  Mayumi Nishimura; Kazuhiro Daino; Maki Fukuda; Ikuya Tanaka; Hitomi Moriyama; Kaye Showler; Yukiko Nishimura; Masaru Takabatake; Toshiaki Kokubo; Atsuko Ishikawa; Kazumasa Inoue; Masahiro Fukushi; Shizuko Kakinuma; Tatsuhiko Imaoka; Yoshiya Shimada
Journal:  PLoS One       Date:  2021-08-13       Impact factor: 3.240

  2 in total

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