Literature DB >> 8032490

Effect of temperature on separation of norgestrel enantiomers by high-performance liquid chromatography.

H Lamparczyk1, P K Zarzycki, J Nowakowska.   

Abstract

The influence of mobile phase composition, concentration of beta-cyclodextrin and temperature on the high-performance liquid chromatographic separation of norgestrel was studied. In studies of the effect of temperature on the enantioselectivity of (+/-)-norgestrel, acetonitrile-water (25:75, v/v) modified by the addition of beta-cyclodextrin (14 mM) was applied as the mobile phase. Enantiomers were detected using UV detection at 240 nm. The capacity factors were measured over a wide range of column temperatures from -5 to 70 degrees C.

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Year:  1994        PMID: 8032490     DOI: 10.1016/0021-9673(94)80133-9

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN: 0021-9673            Impact factor:   4.759


  1 in total

1.  Unexpected differences between planar and column liquid chromatographic retention of 1-acenaphthenol enantiomers controlled by supramolecular interactions involving β-cyclodextrin at subambient temperatures.

Authors:  Hatsuichi Ohta; Elżbieta Włodarczyk; Krzysztof Piaskowski; Aleksandra Kaleniecka; Lucyna Lewandowska; Michał J Baran; Mariusz Wojnicz; Kiyokatsu Jinno; Yoshihiro Saito; Paweł K Zarzycki
Journal:  Anal Bioanal Chem       Date:  2017-03-24       Impact factor: 4.142

  1 in total

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