Literature DB >> 8032203

Role of DNA methylation in the regulation of transcription.

S Eden1, H Cedar.   

Abstract

DNA methylation plays an important role in the regulation of gene expression during development. Methyl moieties at CpG residues suppress transcription by affecting DNA-protein interactions, thus altering the accessibility of genes to trans-acting factors in the cell. Because it works in cis, this mechanism is important in the control of X inactivation and genomic imprinting.

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Year:  1994        PMID： 8032203     DOI： 10.1016/s0959-437x(05)80052-8

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  96 in total

1.  Establishment and maintenance of DNA methylation patterns in mouse Ndn: implications for maintenance of imprinting in target genes of the imprinting center.

Authors:  M L Hanel; R Wevrick
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272

2.  Hypomethylation promotes autonomous endosperm development and rescues postfertilization lethality in fie mutants.

Authors:  R Vinkenoog; M Spielman; S Adams; R L Fischer; H G Dickinson; R J Scott
Journal:  Plant Cell       Date:  2000-11       Impact factor: 11.277

3.  Developmental patterns of chromatin structure and DNA methylation responsible for epigenetic expression of a maize regulatory gene.

Authors:  O A Hoekenga; M G Muszynski; K C Cone
Journal:  Genetics       Date:  2000-08       Impact factor: 4.562

4.  The dominance of alleles controlling self-incompatibility in Brassica pollen is regulated at the RNA level.

Authors:  Hiroshi Shiba; Megumi Iwano; Tetsuyuki Entani; Kyoko Ishimoto; Hiroko Shimosato; Fang-Sik Che; Yoko Satta; Akiko Ito; Yoshinobu Takada; Masao Watanabe; Akira Isogai; Seiji Takayama
Journal:  Plant Cell       Date:  2002-02       Impact factor: 11.277

5.  Molecular mechanisms of gene silencing mediated by DNA methylation.

Authors:  Michela Curradi; Annalisa Izzo; Gianfranco Badaracco; Nicoletta Landsberger
Journal:  Mol Cell Biol       Date:  2002-05       Impact factor: 4.272

Review 6.  Nucleolar dominance: uniparental gene silencing on a multi-megabase scale in genetic hybrids.

Authors:  C S Pikaard
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

7.  Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site.

Authors:  Holly Maier; Jeff Colbert; Daniel Fitzsimmons; Dawn R Clark; James Hagman
Journal:  Mol Cell Biol       Date:  2003-03       Impact factor: 4.272

8.  RNA polymerase I transcription in a Brassica interspecific hybrid and its progenitors: Tests of transcription factor involvement in nucleolar dominance.

Authors:  M Frieman; Z J Chen; J Saez-Vasquez; L A Shen; C S Pikaard
Journal:  Genetics       Date:  1999-05       Impact factor: 4.562

9.  Hepatocyte nuclear factor 1alpha gene inactivation impairs chromatin remodeling and demethylation of the phenylalanine hydroxylase gene.

Authors:  M Pontoglio; D M Faust; A Doyen; M Yaniv; M C Weiss
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

10.  Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome.

Authors:  Bradford Coffee; Fuping Zhang; Stephanie Ceman; Stephen T Warren; Daniel Reines
Journal:  Am J Hum Genet       Date:  2002-09-13       Impact factor: 11.025
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