Literature DB >> 8030938

Lectin effects on HIV-1 infectivity.

L Hammar1, I Hirsch, A Machado, J De Mareuil, J Baillon, J C Chermann.   

Abstract

Lectins with specificity for terminal mannose residues and anti-mannan antibodies are assumed to neutralize HIV-1 by binding to the viral glycoproteins. In this report we demonstrate that one such agents, the lectin from Galanthus nivalis (GNA), blocks infection also at the target cell level.

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Year:  1994        PMID: 8030938     DOI: 10.1111/j.1749-6632.1994.tb38907.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN: 0077-8923            Impact factor:   5.691


  1 in total

1.  A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection.

Authors:  A A Bashirova; T B Geijtenbeek; G C van Duijnhoven; S J van Vliet; J B Eilering; M P Martin; L Wu; T D Martin; N Viebig; P A Knolle; V N KewalRamani; Y van Kooyk; M Carrington
Journal:  J Exp Med       Date:  2001-03-19       Impact factor: 14.307

  1 in total

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