OBJECTIVE: Our purpose was to determine the maternal blood glucose response to food throughout pregnancy. STUDY DESIGN: Forty-five normal, healthy primiparous women with singleton pregnancies were studied longitudinally throughout pregnancy. Blood glucose levels were determined at each stage of pregnancy after a standardized test meal. RESULTS: Fasting plasma glucose decreased throughout gestation and rose again significantly post partum. Glucose values at 30, 60, 90, and 120 minutes after a standardized test meal were similar at all gestational ages studied. CONCLUSIONS: Plasma glucose levels after a physiologic challenge with food do not alter with advancing gestation. This has implications both for the management of insulin-dependent diabetes during pregnancy and for the diagnosis of gestational diabetes.
OBJECTIVE: Our purpose was to determine the maternal blood glucose response to food throughout pregnancy. STUDY DESIGN: Forty-five normal, healthy primiparous women with singleton pregnancies were studied longitudinally throughout pregnancy. Blood glucose levels were determined at each stage of pregnancy after a standardized test meal. RESULTS: Fasting plasma glucose decreased throughout gestation and rose again significantly post partum. Glucose values at 30, 60, 90, and 120 minutes after a standardized test meal were similar at all gestational ages studied. CONCLUSIONS: Plasma glucose levels after a physiologic challenge with food do not alter with advancing gestation. This has implications both for the management of insulin-dependent diabetes during pregnancy and for the diagnosis of gestational diabetes.
Authors: Milana A Bochkur Dratver; Juliana Arenas; Tanayott Thaweethai; Chu Yu; Kaitlyn James; Emily A Rosenberg; Michael J Callahan; Melody Cayford; Jessica S Tangren; Sarah N Bernstein; Marie France Hivert; Ravi Thadhani; Camille E Powe Journal: Diabetologia Date: 2021-12-30 Impact factor: 10.122