Literature DB >> 8030460

A Na:H exchanger subtype mediates volume regulation in bovine corneal epithelial cells.

P Reinach1, V Ganapathy, V Torres-Zamorano.   

Abstract

To identify a role for a Na:H (NHE) exchanger subtype in volume regulation in bovine corneal epithelium, we determined: 1. its sensitivity to inhibition by amiloride analogues 2. the effects of either Cl removal or hypertonicity on the intracellular pH. Our results suggest that volume regulatory responses elicited by stimulation of NHE-2 may help preserve epithelial barrier function in the face of increases in tear film osmolarity.

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Year:  1994        PMID: 8030460     DOI: 10.1007/978-1-4615-2417-5_18

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  2 in total

1.  Characterization of regulatory volume behavior by fluorescence quenching in human corneal epithelial cells.

Authors:  J E Capó-Aponte; P Iserovich; P S Reinach
Journal:  J Membr Biol       Date:  2005-09       Impact factor: 1.843

2.  Hypertonicity-induced p38MAPK activation elicits recovery of corneal epithelial cell volume and layer integrity.

Authors:  V N Bildin; Z Wang; P Iserovich; P S Reinach
Journal:  J Membr Biol       Date:  2003-05-01       Impact factor: 1.843

  2 in total

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