Literature DB >> 802750

DNA repair after UV and gamma irradiation. I. Rat spleen cells.

P Rocchi, P Perocco, S Grilli, G Arfellini, C Franceschi, A M Ferreri, G Prodi.   

Abstract

An in vitro microculture was set up to standardize DNA enzymatic repair in rat spleen lymphocytes after exposure to ultraviolet or gamma rays by measuring the tritiated thymidine uptake. A relation between irradiation dose and DNA repair is always observable when cell viability and scheduled DNA synthesis are taken into account. This micromethod utilizing rat spleen cells appears to be a suitable system for such a study since it permits a satisfactory evaluation of DNA repair.

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Year:  1976        PMID: 802750

Source DB:  PubMed          Journal:  Arch Sci Biol (Bologna)        ISSN: 0004-0169


  1 in total

1.  Effect of pesticides on scheduled and unscheduled DNA synthesis of rat thymocytes and human lymphocytes.

Authors:  P Rocchi; P Perocco; W Alberghini; A Fini; G Prodi
Journal:  Arch Toxicol       Date:  1980-07       Impact factor: 5.153

  1 in total

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