Literature DB >> 8027243

Islet amyloidosis in a patient with chronic massive insulin resistance due to antiinsulin receptor antibodies.

T D O'Brien1, R A Rizza, J A Carney, P C Butler.   

Abstract

We report islet hyperplasia, nesidioblastosis, and abundant islet amyloidosis (derived from islet amyloid polypeptide) in a case of severe insulin resistance due to a circulating antiinsulin receptor antibody. Massive chronic beta-cell stimulation (as well as noninsulin-dependent diabetes mellitus and insulinoma) appears to be associated with islet amyloid.

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Year:  1994        PMID： 8027243     DOI： 10.1210/jcem.79.1.8027243

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN： 0021-972X            Impact factor:   5.958


  5 in total

Review 1.  Nesidioblastosis unravelled.

Authors:  R D Milner
Journal:  Arch Dis Child       Date:  1996-05       Impact factor: 3.791

2.  Human islet amyloid polypeptide expression in COS-1 cells. A model of intracellular amyloidogenesis.

Authors:  T D O'Brien; P C Butler; D K Kreutter; L A Kane; N L Eberhardt
Journal:  Am J Pathol       Date:  1995-09       Impact factor: 4.307

3.  Expression of wild-type and mutant S20G hIAPP in physiologic knock-in mouse models fails to induce islet amyloid formation, but induces mild glucose intolerance.

Authors:  Henry J Hiddinga; Setsuya Sakagashira; Masayuki Ishigame; Pranathi Madde; Tokio Sanke; Kishio Nanjo; Yogish C Kudva; James J Lee; Jan van Deursen; Norman L Eberhardt
Journal:  J Diabetes Investig       Date:  2012-03-28       Impact factor: 4.232

4.  Heterozygous Insulin Receptor (INSR) Mutation Associated with Neonatal Hyperinsulinemic Hypoglycaemia and Familial Diabetes Mellitus: Case Series

Authors:  Aashish Sethi; Nicola Foulds; Sarah Ehtisham; Syed Haris Ahmed; Jayne Houghton; Kevin Colclough; Mohammed Didi; Sarah E. Flanagan; Senthil Senniappan
Journal:  J Clin Res Pediatr Endocrinol       Date:  2020-01-28

5.  Clinical characteristics of insulin resistance syndromes: A nationwide survey in Japan.

Authors:  Takehito Takeuchi; Yasushi Ishigaki; Yushi Hirota; Yutaka Hasegawa; Tohru Yorifuji; Hiroko Kadowaki; Takashi Akamizu; Wataru Ogawa; Hideki Katagiri
Journal:  J Diabetes Investig       Date:  2019-12-05       Impact factor: 4.232
  5 in total

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