Literature DB >> 8025688

recA mutations reduce adherence and colonization by classical and El Tor strains of Vibrio cholerae.

K K Kumar1, R Srivastava, V B Sinha, J Michalski, J B Kaper, B S Srivastava.   

Abstract

Two recA mutants of Vibrio cholerae (classical and El Tor biotypes) were constructed by disruption of the wild-type recA gene with mutated recA sequences of V. cholerae cloned in the suicide vector pGP704. Mutants defective in the recA gene were compared with their respective RecA+ parent strains with regard to their adherence to isolated rabbit intestine and colonization of intestine of infant mice. The recA mutation in V. cholerae was found to diminish adherence and markedly affected colonization.

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Year:  1994        PMID: 8025688     DOI: 10.1099/13500872-140-5-1217

Source DB:  PubMed          Journal:  Microbiology        ISSN: 1350-0872            Impact factor:   2.777


  8 in total

1.  Overexpression of the recA gene decreases oral but not intraperitoneal fitness of Salmonella enterica.

Authors:  Laura Medina-Ruiz; Susana Campoy; Cristina Latasa; Paula Cardenas; Juan Carlos Alonso; Jordi Barbé
Journal:  Infect Immun       Date:  2010-05-10       Impact factor: 3.441

2.  Temperature-dependent hypermutational phenotype in recA mutants of Thermus thermophilus HB27.

Authors:  Pablo Castán; Lorena Casares; Jordi Barbé; José Berenguer
Journal:  J Bacteriol       Date:  2003-08       Impact factor: 3.490

3.  Inactivation of the spirochete recA gene results in a mutant with low viability and irregular nucleoid morphology.

Authors:  Ange-Patricia Tchamedeu Kameni; Evelyne Couture-Tosi; Isabelle Saint-Girons; Mathieu Picardeau
Journal:  J Bacteriol       Date:  2002-01       Impact factor: 3.490

4.  Construction and analysis of a Streptococcus parasanguis recA mutant: homologous recombination is not required for adhesion in an in vitro tooth surface model.

Authors:  E H Froeliger; M Tomich; P Fives-Taylor
Journal:  J Bacteriol       Date:  1999-01       Impact factor: 3.490

5.  Modulating cellular recombination potential through alterations in RecA structure and regulation.

Authors:  Irina V Bakhlanova; Alexandra V Dudkina; Dima M Baitin; Kendall L Knight; Michael M Cox; Vladislav A Lanzov
Journal:  Mol Microbiol       Date:  2010-10-19       Impact factor: 3.501

6.  In Vivo-Expressed Proteins of Virulent Leptospira interrogans Serovar Autumnalis N2 Elicit Strong IgM Responses of Value in Conclusive Diagnosis.

Authors:  Veerapandian Raja; Santhanam Shanmughapriya; Murugesan Kanagavel; Sergey C Artiushin; Sridhar Velineni; John F Timoney; Kalimuthusamy Natarajaseenivasan
Journal:  Clin Vaccine Immunol       Date:  2015-11-25

7.  Preliminary assessment of the safety and immunogenicity of a new CTXPhi-negative, hemagglutinin/protease-defective El Tor strain as a cholera vaccine candidate.

Authors:  J A Benítez; L García; A Silva; H García; R Fando; B Cedré; A Pérez; J Campos; B L Rodríguez; J L Pérez; T Valmaseda; O Pérez; A Pérez; M Ramírez; T Ledón; M D Jidy; M Lastre; L Bravo; G Sierra
Journal:  Infect Immun       Date:  1999-02       Impact factor: 3.441

8.  Transcriptional analysis of the recA gene of Streptococcus thermophilus.

Authors:  Gabriele Giliberti; Loredana Baccigalupi; Angelina Cordone; Ezio Ricca; Maurilio De Felice
Journal:  Microb Cell Fact       Date:  2006-09-14       Impact factor: 5.328

  8 in total

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