Literature DB >> 8025239

GABA-B receptor-mediated spinal inhibition.

D R Curtis1, G Lacey.   

Abstract

The intravenous administration to pentobarbitone-anaesthetized cats of the GABA-B antagonists CGP 46381 and CGP 35348 blocks the longer duration component of the inhibition of lumbar extensor monosynaptic reflexes by tetanic stimulation of low threshold flexor primary afferent fibres. GABA-B receptors thus appear to be associated with this inhibitory process, in addition to bicuculline-sensitive GABA-A receptors associated with shorter duration 'presynaptic' inhibition of reflexes and the depolarization of the terminals of primary afferent fibres.

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Year:  1994        PMID： 8025239     DOI： 10.1097/00001756-199401000-00002

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  11 in total

1.  Heterosynaptic modulation of the dorsal root potential in the turtle spinal cord in vitro.

Authors:  Raúl E Russo; Rodolfo Delgado-Lezama; Jørn Hounsgaard
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2.  5-HT1D receptors inhibit the monosynaptic stretch reflex by modulating C-fiber activity.

Authors:  Ana M Lucas-Osma; Yaqing Li; Katie Murray; Shihao Lin; Sophie Black; Marilee J Stephens; Andrew H Ahn; C J Heckman; Keith K Fenrich; Karim Fouad; David J Bennett
Journal:  J Neurophysiol       Date:  2019-01-09       Impact factor: 2.714

3.  An in vivo electrophysiological investigation of group Ia afferent fibres and ventral horn terminations in the cat spinal cord.

Authors:  D R Curtis; B D Gynther; D T Beattie; G Lacey
Journal:  Exp Brain Res       Date:  1995       Impact factor: 1.972

Review 4.  Neuroanatomy of the pain system and of the pathways that modulate pain.

Authors:  W D Willis; K N Westlund
Journal:  J Clin Neurophysiol       Date:  1997-01       Impact factor: 2.177

5.  Evaluation of peripheral versus central effects of GABA(B) receptor activation using a novel, positive allosteric modulator of the GABA(B) receptor ADX71943, a pharmacological tool compound with a fully peripheral activity profile.

Authors:  M Kalinichev; T Donovan-Rodriguez; F Girard; E Riguet; M Rouillier; B Bournique; H Haddouk; V Mutel; S Poli
Journal:  Br J Pharmacol       Date:  2014-09-05       Impact factor: 8.739

Review 6.  Synaptic control of motoneuronal excitability.

Authors:  J C Rekling; G D Funk; D A Bayliss; X W Dong; J L Feldman
Journal:  Physiol Rev       Date:  2000-04       Impact factor: 37.312

Review 7.  Intrathecal baclofen: effects on spasticity, pain, and consciousness in disorders of consciousness and locked-in syndrome.

Authors:  Francesca Pistoia; Simona Sacco; Marco Sarà; Marco Franceschini; Antonio Carolei
Journal:  Curr Pain Headache Rep       Date:  2015-01

8.  Phosphinic acid derivatives as baclofen agonists and antagonists in the mammalian spinal cord: an in vivo study.

Authors:  G Lacey; D R Curtis
Journal:  Exp Brain Res       Date:  1994       Impact factor: 1.972

9.  The role of glutamate and GABA receptors in the generation of dorsal root reflexes by acute arthritis in the anaesthetized rat.

Authors:  H Rees; K A Sluka; K N Westlund; W D Willis
Journal:  J Physiol       Date:  1995-04-15       Impact factor: 5.182

10.  Extrasynaptic α5GABAA receptors on proprioceptive afferents produce a tonic depolarization that modulates sodium channel function in the rat spinal cord.

Authors:  Ana M Lucas-Osma; Yaqing Li; Shihao Lin; Sophie Black; Rahul Singla; Karim Fouad; Keith K Fenrich; David J Bennett
Journal:  J Neurophysiol       Date:  2018-09-26       Impact factor: 2.714
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