Literature DB >> 802510

Peptidyl transferase centre of bacterial ribosomes: substrate specificity and binding sites.

A A Krayevsky, M K Kukhanova, B P Gottikh.   

Abstract

A detailed scheme of the Peptidyl Transferase Centre of bacterial ribosomes is proposed by summarizing the literature data on the substrate specificity of the acceptor and donor sites. According to the proposed scheme only the elements of the donor and acceptor having a stable structure bind with the ribosome. The present paper proposes such main elements for the donor and acceptor.

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Year:  1975        PMID： 802510      PMCID： PMC343590          DOI： 10.1093/nar/2.12.2223

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  36 in total

1.  On the mechanism of peptide bond synthesis in the ribosome. 3'-O-phenylalanyl-2'-O-methyladenosine as a peptide acceptor.

Authors:  V A. Pozdnyakov; Yu V. Mitin; M K. Kukhanova; L V. Nikolaeva; A A. Krayevsky; B P. Gottikh
Journal:  FEBS Lett       Date:  1972-08-01       Impact factor: 4.124

2.  3'(2')-O-Aminoacylnucleotides as polypeptide acceptors at the ribosomal peptidyltransferase center.

Authors:  B P. Gottikh; L V. Nikolayeva; A A. Krayevski; L L. Kisselev
Journal:  FEBS Lett       Date:  1970-04-02       Impact factor: 4.124

3.  PUROMYCIN INHIBITION OF PROTEIN SYNTHESIS: INCORPORATION OF PUROMYCIN INTO PEPTIDE CHAINS.

Authors:  D NATHANS
Journal:  Proc Natl Acad Sci U S A       Date:  1964-04       Impact factor: 11.205

4.  Ribosomal peptidyl transferase: recognition points on the 3'-terminus of AA tRNA.

Authors:  D Ringer; S Chládek
Journal:  FEBS Lett       Date:  1974-02-01       Impact factor: 4.124

5.  2' (3')-O-N-formylmethionyl)-adenosine-5'-phosphate, a new donor substrate in peptidyl transferase catalyzed reactions.

Authors:  J Cerná; I Rychlík; A A Krayevsky; B P Gottikh
Journal:  FEBS Lett       Date:  1973-12-01       Impact factor: 4.124

6.  Ribosome-catalyzed ester formation.

Authors:  S Fahnestock; H Neumann; V Shashoua; A Rich
Journal:  Biochemistry       Date:  1970-06-09       Impact factor: 3.162

7.  Stereochemistry of nucleic acids and their constituents. 13. The crystal and molecular structure of 3'-O-acetyladenosine. Conformational analysis of nucleosides and nucleotides with syn glycosidic torsional angle.

Authors:  S T Rao; M Sundaralingam
Journal:  J Am Chem Soc       Date:  1970-08-12       Impact factor: 15.419

8.  Inhibition of protein synthesis by aminoacyl 3'-(2')-adenosine.

Authors:  J P Waller; T Erdös; F Lemoine; S Guttmann; E Sandrin
Journal:  Biochim Biophys Acta       Date:  1966-06-22

9.  Puromycin analogs. Synthesis and biological activity of 5'-deoxypuromycin and its aminonucleoside, 6-dimethylamino-9(3'-amin-3',5-dideoxy-beta-D-ribofuranosyl)purine.

Authors:  R G Almquist; R Vince
Journal:  J Med Chem       Date:  1973-12       Impact factor: 7.446

10.  Puromycin analogs. Aminoacyl derivatives of 9-(3'-amino-3'-deoxy-beta-D-arabino-furanosyl)adenine.

Authors:  L V Fisher; W W Lee; L Goodman
Journal:  J Med Chem       Date:  1970-07       Impact factor: 7.446
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  2 in total

1.  Synthesis of acylamino acid esters of nucleoside 5'-phosphates and their investigation with PMR and CD spectra.

Authors:  A V Azhayev; S V Popovkina; N B Tarussova; M P Kirpichnikov; V L Florentiev; A A Krayevsky; M K Kukhanova; B P Gottikh
Journal:  Nucleic Acids Res       Date:  1977-07       Impact factor: 16.971

2.  Catalysis of the peptide bond formation by 50 S subunits of E. coli ribosomes with N-(formyl) methionine ester of adenylic acid as peptide donor.

Authors:  V V Kotusov; M K Kukhanova; A A Krayevsky; B P Gottikh
Journal:  Mol Biol Rep       Date:  1976-11       Impact factor: 2.316
  2 in total

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