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Literature DB >> 8024816

The regulation of B- and T-lymphocyte activation by the transmembrane protein tyrosine phosphatase CD45.

Abstract

The expression of transmembrane protein tyrosine phosphatase CD45 is required for antigen-induced activation of T and B lymphocytes. During the past year, advances have been made in our understanding of CD45 regulation and its role in regulating Src-family members. The importance of CD45 in thymocyte maturation has been demonstrated through the generation of CD45-knockout mice.

Entities: Gene Species

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Year: 1994 PMID： 8024816 DOI： 10.1016/0955-0674(94)90143-0

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

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Cited

6 in total

Review 1. Pulling strings below the surface: hormone receptor signaling through inhibition of protein tyrosine phosphatases.

Authors: X Espanel; S Wälchli; R P Gobert; M El Alama; M L Curchod; N Gullu-Isler; R Hooft van Huijsduijnen
Journal: Endocrine Date: 2001-06 Impact factor: 3.633

2. Physical and epitope analysis of a recombinant human T-cell receptor V alpha/V beta construct support the similarity to immunoglobulin.

Authors: D F Lake; S Helgerson; W J Landsperger; J J Marchalonis
Journal: J Protein Chem Date: 1997-05

6. Shigella infection induces cellular activation of T and B cells and distinct species-related changes in peripheral blood lymphocyte subsets during the course of the disease.

Authors: D Islam; P K Bardhan; A A Lindberg; B Christensson
Journal: Infect Immun Date: 1995-08 Impact factor: 3.441

6 in total

The regulation of B- and T-lymphocyte activation by the transmembrane protein tyrosine phosphatase CD45.

Review 1. Pulling strings below the surface: hormone receptor signaling through inhibition of protein tyrosine phosphatases.

2. Physical and epitope analysis of a recombinant human T-cell receptor V alpha/V beta construct support the similarity to immunoglobulin.

3. SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription.

4. A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation.

5. Genetic basis of antigenic differences between three alleles of Ly5 (CD45) in mice.

6. Shigella infection induces cellular activation of T and B cells and distinct species-related changes in peripheral blood lymphocyte subsets during the course of the disease.