Literature DB >> 8024806

Structural and functional basis for hormone binding and receptor oligomerization.

J A Wells1.   

Abstract

Most single-pass transmembrane receptors undergo a change in oligomeric state upon hormone binding. Recent mutational, biophysical and structural studies of the human growth hormone and tumor necrosis factor receptor complexes have revealed much about the mechanisms and molecular bases for binding and oligomerization. Principles learned from these examples and others should apply to many other hormone-receptor complexes.

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Year:  1994        PMID: 8024806     DOI: 10.1016/0955-0674(94)90132-5

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN: 0955-0674            Impact factor:   8.382


  15 in total

1.  A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix.

Authors:  Bin Xu; Qing-Xin Hua; Satoe H Nakagawa; Wenhua Jia; Ying-Chi Chu; Panayotis G Katsoyannis; Michael A Weiss
Journal:  Protein Sci       Date:  2002-01       Impact factor: 6.725

2.  Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry.

Authors:  J C Whitbeck; C Peng; H Lou; R Xu; S H Willis; M Ponce de Leon; T Peng; A V Nicola; R I Montgomery; M S Warner; A M Soulika; L A Spruce; W T Moore; J D Lambris; P G Spear; G H Cohen; R J Eisenberg
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

3.  Comparative study of the conformational lock, dissociative thermal inactivation and stability of euphorbia latex and lentil seedling amine oxidases.

Authors:  M Amani; A A Moosavi-Movahedi; G Floris; S Longu; A Mura; S Z Moosavi-Nejad; A A Saboury; F Ahmad
Journal:  Protein J       Date:  2005-04       Impact factor: 2.371

Review 4.  The two-component signaling pathway of bacterial chemotaxis: a molecular view of signal transduction by receptors, kinases, and adaptation enzymes.

Authors:  J J Falke; R B Bass; S L Butler; S A Chervitz; M A Danielson
Journal:  Annu Rev Cell Dev Biol       Date:  1997       Impact factor: 13.827

5.  Ligand binding to heparan sulfate proteoglycans induces their aggregation and distribution along actin cytoskeleton.

Authors:  R G Martinho; S Castel; J Ureña; M Fernández-Borja; R Makiya; G Olivecrona; M Reina; A Alonso; S Vilaró
Journal:  Mol Biol Cell       Date:  1996-11       Impact factor: 4.138

Review 6.  Binding in the growth hormone receptor complex.

Authors:  J A Wells
Journal:  Proc Natl Acad Sci U S A       Date:  1996-01-09       Impact factor: 11.205

7.  tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c.

Authors:  M C Wei; T Lindsten; V K Mootha; S Weiler; A Gross; M Ashiya; C B Thompson; S J Korsmeyer
Journal:  Genes Dev       Date:  2000-08-15       Impact factor: 11.361

8.  Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation.

Authors:  G Venkataraman; V Sasisekharan; A B Herr; D M Ornitz; G Waksman; C L Cooney; R Langer; R Sasisekharan
Journal:  Proc Natl Acad Sci U S A       Date:  1996-01-23       Impact factor: 11.205

9.  ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization.

Authors:  Wenxiang Sun; Yang Li; Lu Chen; Huihui Chen; Fuping You; Xiang Zhou; Yi Zhou; Zhonghe Zhai; Danying Chen; Zhengfan Jiang
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-11       Impact factor: 11.205

10.  A sequential dimerization mechanism for erythropoietin receptor activation.

Authors:  D J Matthews; R S Topping; R T Cass; L B Giebel
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-03       Impact factor: 11.205

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