Literature DB >> 8024091

Survival and quality of life after portal blood flow preserving procedures in patients with portal hypertension and liver cirrhosis.

H Orozco1, M A Mercado, T Takahashi, G Rojas, J Hernández, M Tielve.   

Abstract

Between 1979 and 1991, 156 patients with histologically proven liver cirrhosis, good liver function, and bleeding portal hypertension underwent operation with portal blood flow preserving procedures (selective shunts: 101; Sugiura-Futagawa: 55). Long-term results of the procedures and the quality of life of the 145 patients who survived the operation were studied. During the observation period (range 3 to 156 months), 28 patients died. The main causes of death were liver failure and hepatoma. Twenty-three patients were lost for follow-up. Twenty-six patients (18%) developed 1 or more encephalopathic episodes. Four patients (3%) experienced rebleeding. One hundred eight patients (74%) had a good quality of life, and 26 (18%) had a poor quality of life. Eleven (15%) of 73 patients with a history of alcoholism continued drinking. Five-year survival for the selective shunt group was 81% and for the devascularization group was 83%. In 81% of the patients, portal blood flow was maintained. It is concluded that both procedures are effective in the long-term. Most patients are able to rehabilitate from the use of alcohol, and most of them have a good quality of life. For patients with good liver function (whose main problem is bleeding), surgery is the best choice of treatment.

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Year:  1994        PMID: 8024091     DOI: 10.1016/s0002-9610(05)80062-5

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  4 in total

1.  An evaluation of splenopancreatic disconnection as a modification of the distal splenorenal shunt, studied in nonalcoholic patients by sequential angiography.

Authors:  A Nishioka; H Ashida; M Nishiwaki; J Utsunomiya
Journal:  Surg Today       Date:  1997       Impact factor: 2.549

2.  Diminished morbidity and mortality in portal hypertension surgery: relocation in the therapeutic armamentarium.

Authors:  M A Mercado; H Orozco; F J Ramírez-Cisneros; C A Hinojosa; J J Plata; J Alvarez-Tostado
Journal:  J Gastrointest Surg       Date:  2001 Sep-Oct       Impact factor: 3.452

3.  Small-diameter mesocaval shunts: a 10-year evaluation.

Authors:  M A Mercado; H Orozco; E Guillén-Navarro; E Acosta; L M López-Martínez; C Hinojosa; J Hernández; M Tielve
Journal:  J Gastrointest Surg       Date:  2000 Sep-Oct       Impact factor: 3.452

4.  The surgical treatment for portal hypertension: a systematic review and meta-analysis.

Authors:  Lanning Yin; Haipeng Liu; Youcheng Zhang; Wen Rong
Journal:  ISRN Gastroenterol       Date:  2013-01-27
  4 in total

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