| Literature DB >> 8022781 |
B R Dworkin1, T Elbert, H Rau, N Birbaumer, P Pauli, C Droste, C H Brunia.
Abstract
Activating the arterial baroreceptors blunts pain sensation and produces other forms of central nervous system inhibition in animals. These effects may be important to blood pressure regulation but have not been rigorously verified in humans. We describe (i) a noninvasive behaviorally unbiased method for baroreceptor stimulation and (ii) the application of this method to measurement of baroreceptor-mediated attenuation of pain perception and of the Achilles tendon reflex. The findings are relevant to basic mechanisms of blood pressure stabilization and cardiovascular reactivity and may also have implications for noncompliance with antihypertensive medications and for the pathophysiology of essential hypertension.Entities:
Mesh:
Year: 1994 PMID: 8022781 PMCID: PMC44195 DOI: 10.1073/pnas.91.14.6329
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205