Literature DB >> 8021912

2-Azetidinones as inhibitors of cholesterol absorption.

D A Burnett1, M A Caplen, H R Davis, R E Burrier, J W Clader.   

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Year:  1994        PMID： 8021912     DOI： 10.1021/jm00038a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  10 in total

Review 1.  The discovery of first-in-class drugs: origins and evolution.

Authors:  Jörg Eder; Richard Sedrani; Christian Wiesmann
Journal:  Nat Rev Drug Discov       Date:  2014-07-18       Impact factor: 84.694

2.  Modern Multicomponent Reactions for better Drug Syntheses**

Authors:  Tryfon Zarganes-Tzitzikas; Alexander Dömling
Journal:  Org Chem Front       Date:  2014-09-01       Impact factor: 5.281

3.  Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663.

Authors:  M van Heek; C Farley; D S Compton; L Hoos; K B Alton; E J Sybertz; H R Davis
Journal:  Br J Pharmacol       Date:  2000-04       Impact factor: 8.739

4.  Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition.

Authors:  Soo Hyun Kim; Gyuri Kim; Dai Hoon Han; Milim Lee; Irene Kim; Bohkyung Kim; Kook Hwan Kim; Young-Mi Song; Jeong Eun Yoo; Hye Jin Wang; Soo Han Bae; Yong-Ho Lee; Byung-Wan Lee; Eun Seok Kang; Bong-Soo Cha; Myung-Shik Lee
Journal:  Autophagy       Date:  2017-09-21       Impact factor: 16.016

5.  SREBP2 mediates the modulation of intestinal NPC1L1 expression by curcumin.

Authors:  Pradeep Kumar; Pooja Malhotra; Ke Ma; Amika Singla; Omar Hedroug; Seema Saksena; Pradeep K Dudeja; Ravinder K Gill; Waddah A Alrefai
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2011-04-28       Impact factor: 4.052

6.  Ezetimibe: its novel effects on the prevention and the treatment of cholesterol gallstones and nonalcoholic Fatty liver disease.

Authors:  Ornella de Bari; Brent A Neuschwander-Tetri; Min Liu; Piero Portincasa; David Q-H Wang
Journal:  J Lipids       Date:  2011-11-03

7.  Fungal biotransformation of ezetimibe.

Authors:  Irfan Pervaiz; Saeed Ahmad; Farhan Hameed Khaliq; Adeel Arshad; Muhammad Imran; Barkat Ali Khan; Aftab Ullah; Usman Ali; Kashif Iqbal; Muhammad Usman; Hafsa Bibi; Najm Ul Hassan Khan; Wajahat Mahmood
Journal:  Biotechnol Biotechnol Equip       Date:  2014-11-17       Impact factor: 1.632

8.  Fomiroid A, a novel compound from the mushroom Fomitopsis nigra, inhibits NPC1L1-mediated cholesterol uptake via a mode of action distinct from that of ezetimibe.

Authors:  Tomohiro Chiba; Tsuyoshi Sakurada; Rie Watanabe; Kohji Yamaguchi; Yasuhisa Kimura; Noriyuki Kioka; Hirokazu Kawagishi; Michinori Matsuo; Kazumitsu Ueda
Journal:  PLoS One       Date:  2014-12-31       Impact factor: 3.240

9.  Alphataxin, an Orally Available Small Molecule, Decreases LDL Levels in Mice as a Surrogate for the LDL-Lowering Activity of Alpha-1 Antitrypsin in Humans.

Authors:  Cynthia L Bristow; Ronald Winston
Journal:  Front Pharmacol       Date:  2021-06-09       Impact factor: 5.810

10.  Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors.

Authors:  Tonko Dražić; Krešimir Molčanov; Vinay Sachdev; Martina Malnar; Silva Hećimović; Jay V Patankar; Sascha Obrowsky; Sanja Levak-Frank; Ivan Habuš; Dagmar Kratky
Journal:  Eur J Med Chem       Date:  2014-10-07       Impact factor: 6.514
  10 in total

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