Literature DB >> 8021793

Electrocardiographic findings in Rett syndrome: an explanation for sudden death?

E A Sekul1, J P Moak, R J Schultz, D G Glaze, J K Dunn, A K Percy.   

Abstract

Girls with Rett syndrome had significantly longer corrected QT intervals (p < 0.001) and more T-wave abnormalities (p < 0.001) than were found in age-matched healthy girls. With advancing stages of the syndrome, the proportion of corrected QT interval prolongations and T-wave changes increased. The findings suggest a possible cardiac basis for sudden, unexpected death in Rett syndrome.

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Year:  1994        PMID: 8021793     DOI: 10.1016/s0022-3476(94)70128-8

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  28 in total

1.  Clinical profile of five patients with Rett syndrome and literature review.

Authors:  Riaz Ahmed
Journal:  Oman Med J       Date:  2007-10

Review 2.  Rett syndrome and MeCP2: linking epigenetics and neuronal function.

Authors:  Mona D Shahbazian; Huda Y Zoghbi
Journal:  Am J Hum Genet       Date:  2002-11-19       Impact factor: 11.025

Review 3.  Rett syndrome: clinical review and genetic update.

Authors:  L S Weaving; C J Ellaway; J Gécz; J Christodoulou
Journal:  J Med Genet       Date:  2005-01       Impact factor: 6.318

Review 4.  Cardiac disease and Rett syndrome.

Authors:  M Acampa; F Guideri
Journal:  Arch Dis Child       Date:  2006-05       Impact factor: 3.791

5.  Methyl-CpG binding-protein 2 function in cholinergic neurons mediates cardiac arrhythmogenesis.

Authors:  José A Herrera; Christopher S Ward; Xander H T Wehrens; Jeffrey L Neul
Journal:  Hum Mol Genet       Date:  2016-11-15       Impact factor: 6.150

Review 6.  Rett syndrome.

Authors:  A Clarke
Journal:  J Med Genet       Date:  1996-08       Impact factor: 6.318

7.  Autonomic dysfunction and sudden death in patients with Rett syndrome: a systematic review

Authors:  Jatinder Singh; Evamaria Lanzarini; Paramala Santosh
Journal:  J Psychiatry Neurosci       Date:  2020-05-01       Impact factor: 6.186

8.  Prolonged QT interval in Rett syndrome.

Authors:  C J Ellaway; G Sholler; H Leonard; J Christodoulou
Journal:  Arch Dis Child       Date:  1999-05       Impact factor: 3.791

Review 9.  Evaluation of current pharmacological treatment options in the management of Rett syndrome: from the present to future therapeutic alternatives.

Authors:  Christopher A Chapleau; Jane Lane; Lucas Pozzo-Miller; Alan K Percy
Journal:  Curr Clin Pharmacol       Date:  2013-11

Review 10.  Cardiorespiratory coupling in health and disease.

Authors:  Alfredo J Garcia; Jenna E Koschnitzky; Tatiana Dashevskiy; Jan-Marino Ramirez
Journal:  Auton Neurosci       Date:  2013-03-13       Impact factor: 3.145

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