Literature DB >> 8021378

Kava dermopathy.

S A Norton1, P Ruze.   

Abstract

Kava is a psychoactive beverage used ceremonially for thousands of years by Pacific Islanders. Kava is made from the root of the pepper plant, Piper methysticum, found in Polynesia, Melanesia, and Micronesia. The beverage is a nonfermented depressant with complex neuropharmacologic properties that causes a tranquil state of intoxication. Kava also affects the skin, causing a peculiar scaly eruption. The cutaneous effects were first reported by members of Captain James Cook's Pacific expeditions, but they have never been described in dermatologic literature. Heavy kava drinkers acquire a reversible ichthyosiform eruption, kava dermopathy. The cause is unknown but may relate to interference with cholesterol metabolism. Today kava is used across the Pacific in both traditional ceremonies and informal social events. In Western nations, kava is sold as a relaxant by health food stores. This article explores the history of kava dermopathy from Cook's early reports to its presence today.

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Year:  1994        PMID: 8021378     DOI: 10.1016/s0190-9622(94)70142-3

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  17 in total

1.  Cranberry, feverfew, horse chestnut, and kava.

Authors:  M D Rotblatt
Journal:  West J Med       Date:  1999-09

2.  Herbal Medicine: Is it an Alternative or an Unknown? A Brief Review of Popular Herbals Used by Patients in a Pain and Symptom Management Practice Setting.

Authors: 
Journal:  Curr Rev Pain       Date:  1999

3.  Pacific island 'Awa (Kava) extracts, but not isolated kavalactones, promote proinflammatory responses in model mast cells.

Authors:  Lori M N Shimoda; Christy Park; Alexander J Stokes; Henry Halenani Gomes; Helen Turner
Journal:  Phytother Res       Date:  2012-04-04       Impact factor: 5.878

4.  Immunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extract.

Authors:  Natasha P Clayton; Katsuhiko Yoshizawa; Grace E Kissling; Leo T Burka; Po-Chuen Chan; Abraham Nyska
Journal:  Exp Toxicol Pathol       Date:  2006-10-23

Review 5.  Therapeutic potential of kava in the treatment of anxiety disorders.

Authors:  Yadhu N Singh; Nirbhay N Singh
Journal:  CNS Drugs       Date:  2002       Impact factor: 5.749

6.  A systematic review of the safety of kava extract in the treatment of anxiety.

Authors:  Clare Stevinson; Alyson Huntley; Edzard Ernst
Journal:  Drug Saf       Date:  2002       Impact factor: 5.606

7.  Liver toxicity and carcinogenicity in F344/N rats and B6C3F1 mice exposed to Kava Kava.

Authors:  Mamta Behl; Abraham Nyska; Rajendra S Chhabra; Gregory S Travlos; Laurene M Fomby; Barney R Sparrow; Milton R Hejtmancik; Po C Chan
Journal:  Food Chem Toxicol       Date:  2011-08-18       Impact factor: 6.023

8.  How does male ritual behavior vary across the lifespan? An examination of Fijian kava ceremonies.

Authors:  John H Shaver; Richard Sosis
Journal:  Hum Nat       Date:  2014-03

9.  Phototoxicity of kava - formation of reactive oxygen species leading to lipid peroxidation and DNA damage.

Authors:  Qingsu Xia; Hsiu-Mei Chiang; Yu-Ting Zhou; Jun-Jie Yin; Fang Liu; Cheng Wang; Lei Guo; Peter P Fu
Journal:  Am J Chin Med       Date:  2012       Impact factor: 4.667

10.  Complementary and alternative medicine use by otolaryngology patients: a paradigm for practitioners in all surgical specialties.

Authors:  Muhammad Shakeel; Aaron Trinidade; Kim W Ah-See
Journal:  Eur Arch Otorhinolaryngol       Date:  2009-09-22       Impact factor: 2.503

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