Literature DB >> 8020936

Transforming growth factor receptor gene TGFBR2 maps to human chromosome band 3p22.

S Mathew1, V V Murty, S Cheifetz, D George, J Massagué, R S Chaganti.   

Abstract

In this study, we map the chromosomal position of the gene that encodes the type II receptor of TGF-beta (HGM symbol TGFBR2), a multifunctional regulator of cell proliferation and differentiation. Using a full-length cDNA and a genomic probe in Southern blot analysis of a human x rodent somatic cell hybrid panel and by direct fluorescence in situ hybridization to normal metaphase chromosomes, we show that the TGFBR2 gene maps to 3p22.

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Year:  1994        PMID： 8020936     DOI： 10.1006/geno.1994.1134

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  10 in total

1.  Dynamics of protein 27 of avian leukosis virus and transforming growth factor beta2 in lymphoid leukosis susceptible and resistant broiler chicken breeding stock.

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Journal:  Vet Res Commun       Date:  1999-05       Impact factor: 2.459

2.  Chromosomal localization of three human genes encoding members of the TGF-beta superfamily of type I serine/threonine kinase receptors.

Authors:  E Röijer; K Miyazono; A K Aström; A Geurts van Kessel; P ten Dijke; G Stenman
Journal:  Mamm Genome       Date:  1998-03       Impact factor: 2.957

Review 3.  Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs.

Authors:  I F Dunn; O Heese; P M Black
Journal:  J Neurooncol       Date:  2000 Oct-Nov       Impact factor: 4.130

4.  Nonrandom cytogenetic alterations in hepatocellular carcinoma from transgenic mice overexpressing c-Myc and transforming growth factor-alpha in the liver.

Authors:  L M Sargent; X Zhou; C L Keck; N D Sanderson; D B Zimonjic; N C Popescu; S S Thorgeirsson
Journal:  Am J Pathol       Date:  1999-04       Impact factor: 4.307

5.  A dominant inhibitory mutant of the type II transforming growth factor beta receptor in the malignant progression of a cutaneous T-cell lymphoma.

Authors:  P I Knaus; D Lindemann; J F DeCoteau; R Perlman; H Yankelev; M Hille; M E Kadin; H F Lodish
Journal:  Mol Cell Biol       Date:  1996-07       Impact factor: 4.272

6.  Recurrent and nonrandom DNA copy number and chromosome alterations in Myc transgenic mouse model for hepatocellular carcinogenesis: implications for human disease.

Authors:  Drazen B Zimonjic; Veronika Ullmannova-Benson; Valentina M Factor; Snorri S Thorgeirsson; Nicholas C Popescu
Journal:  Cancer Genet Cytogenet       Date:  2009-05

7.  Chromosome 3 allelic losses and microsatellite alterations in transitional cell carcinoma of the urinary bladder.

Authors:  M Li; Z F Zhang; V E Reuter; C Cordon-Cardo
Journal:  Am J Pathol       Date:  1996-07       Impact factor: 4.307

8.  A sporadic case of Loeys-Dietz syndrome type I with two novel mutations of the TGFBR2 gene.

Authors:  Jung Sook Ha; Yeo Hyang Kim
Journal:  Korean J Pediatr       Date:  2011-06-30

9.  Resequencing of genes for transforming growth factor beta1 (TGFB1) type 1 and 2 receptors (TGFBR1, TGFBR2), and association analysis of variants with diabetic nephropathy.

Authors:  Amy Jayne McKnight; David A Savage; Chris C Patterson; Denise Sadlier; A Peter Maxwell
Journal:  BMC Med Genet       Date:  2007-02-23       Impact factor: 2.103

Review 10.  Transforming growth factor Beta family: insight into the role of growth factors in regulation of fracture healing biology and potential clinical applications.

Authors:  Łukasz A Poniatowski; Piotr Wojdasiewicz; Robert Gasik; Dariusz Szukiewicz
Journal:  Mediators Inflamm       Date:  2015-01-29       Impact factor: 4.711
  10 in total

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