Literature DB >> 8020531

Effect modelling for drugs undergoing enterohepatic circulation.

P Höglund1, M Ohlin.   

Abstract

A multi-compartment pharmacokinetic model with enterohepatic circulation, was used in simulations and in a clinical trial with morphine. A hypothetical effect compartment was linked to either the central or the peripheral disposition compartment.

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Year:  1993        PMID： 8020531     DOI： 10.1007/BF03190182

Source DB:  PubMed          Journal:  Eur J Drug Metab Pharmacokinet        ISSN： 0378-7966            Impact factor:   2.441


  12 in total

1.  Influence of cholestasis on drug elimination: pharmacokinetics.

Authors:  L I Harrison; M Gibaldi
Journal:  J Pharm Sci       Date:  1976-09       Impact factor: 3.534

2.  A variable reabsorption time-delay model for pharmacokinetics of drugs.

Authors:  C Labat; K Mansour; M F Malmary; M Terrissol; J Oustrin
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1987 Apr-Jun       Impact factor: 2.441

3.  Mathematical treatment of linear mammillary models using inverse Laplace transforms.

Authors:  G E Haborak; J D Benmaman; J W Warren
Journal:  J Pharm Sci       Date:  1979-07       Impact factor: 3.534

4.  Estimation of area under the curve for drugs subject to enterohepatic cycling.

Authors:  T A Shepard; R H Reuning; L J Aarons
Journal:  J Pharmacokinet Biopharm       Date:  1985-12

5.  A time-lag model for pharmacokinetics of drugs subject to enterohepatic circulation.

Authors:  J L Steimer; Y Plusquellec; A Guillaume; J F Boisvieux
Journal:  J Pharm Sci       Date:  1982-03       Impact factor: 3.534

Review 6.  Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models.

Authors:  N H Holford; L B Sheiner
Journal:  Clin Pharmacokinet       Date:  1981 Nov-Dec       Impact factor: 6.447

7.  Pharmacokinetics of doxycycline reabsorption.

Authors:  P V Pedersen; R Miller
Journal:  J Pharm Sci       Date:  1980-02       Impact factor: 3.534

8.  Simultaneous pharmacokinetic and pharmacodynamic modeling.

Authors:  W A Colburn
Journal:  J Pharmacokinet Biopharm       Date:  1981-06

9.  Pharmacokinetic interpretation of the enterohepatic recirculation and first-pass elimination of morphine in the rat.

Authors:  B E Dahlström; L K Paalzow
Journal:  J Pharmacokinet Biopharm       Date:  1978-12

10.  Morphine pharmacokinetics and effects on salivation and continuous reaction times in healthy volunteers.

Authors:  D Westerling; L Frigren; P Höglund
Journal:  Ther Drug Monit       Date:  1993-10       Impact factor: 3.681
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  4 in total

Review 1.  Enterohepatic circulation: physiological, pharmacokinetic and clinical implications.

Authors:  Michael S Roberts; Beatrice M Magnusson; Frank J Burczynski; Michael Weiss
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

2.  A quantitative enterohepatic circulation model: development and evaluation with tesofensine and meloxicam.

Authors:  Thorsten Lehr; Alexander Staab; Christiane Tillmann; Dirk Trommeshauser; Hans-Guenter Schaefer; Charlotte Kloft
Journal:  Clin Pharmacokinet       Date:  2009       Impact factor: 6.447

Review 3.  Methods to evaluate biliary excretion of drugs in humans: an updated review.

Authors:  Giulia Ghibellini; Elaine M Leslie; Kim L R Brouwer
Journal:  Mol Pharm       Date:  2006 May-Jun       Impact factor: 4.939

4.  Pharmacogenetic pathway analysis of irinotecan.

Authors:  G L Rosner; J C Panetta; F Innocenti; M J Ratain
Journal:  Clin Pharmacol Ther       Date:  2008-04-16       Impact factor: 6.875
  4 in total

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