Literature DB >> 8019976

Differences in sensitivity to farnesol toxicity between neoplastically- and non-neoplastically-derived cells in culture.

I Adany1, E M Yazlovitskaya, J S Haug, P A Voziyan, G Melnykovych.   

Abstract

Six neoplastically-derived cell lines and three cell lines derived from normal tissues were compared for their sensitivity to isoprenoid trans-trans farnesol. Assays of cell numbers and of protein concentrations per culture revealed greater sensitivity of neoplastic cells than of the normal cells. Similar differences were obtained from the comparison of incorporation of [methyl-3H]choline into cellular lipids, with neoplastic cells showing greater inhibition than normal cells.

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Year:  1994        PMID： 8019976     DOI： 10.1016/0304-3835(94)90257-7

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  8 in total

1.  Farnesol-induced cell death and stimulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in tobacco cv bright yellow-2 cells.

Authors:  A Hemmerlin; T J Bach
Journal:  Plant Physiol       Date:  2000-08       Impact factor: 8.340

2.  Inhibition of pancreatic cancer growth by the dietary isoprenoids farnesol and geraniol.

Authors:  Y D Burke; M J Stark; S L Roach; S E Sen; P L Crowell
Journal:  Lipids       Date:  1997-02       Impact factor: 1.880

3.  An Approach to Minimize Tumour Proliferation by Reducing the Formation of Components for Cell Membrane.

Authors:  Inmaculada de Dios-Pérez; Álvaro González-Garcinuño; Eva María Martín Del Valle
Journal:  Molecules       Date:  2022-04-24       Impact factor: 4.927

4.  Isoprenoid alcohols restore protein isoprenylation in a time-dependent manner independent of protein synthesis.

Authors:  Susan E Ownby; Raymond J Hohl
Journal:  Lipids       Date:  2003-07       Impact factor: 1.880

5.  NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway.

Authors:  Joung Hyuck Joo; Anton M Jetten
Journal:  J Biol Chem       Date:  2008-04-18       Impact factor: 5.157

6.  Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis.

Authors:  Thomas A Lagace; Jessica R Miller; Neale D Ridgway
Journal:  Mol Cell Biol       Date:  2002-07       Impact factor: 4.272

Review 7.  Molecular mechanisms involved in farnesol-induced apoptosis.

Authors:  Joung Hyuck Joo; Anton M Jetten
Journal:  Cancer Lett       Date:  2009-06-10       Impact factor: 8.679

8.  Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents.

Authors:  Anna Gliszczyńska; Natalia Niezgoda; Witold Gładkowski; Marta Czarnecka; Marta Świtalska; Joanna Wietrzyk
Journal:  PLoS One       Date:  2016-06-16       Impact factor: 3.240
  8 in total

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